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EMD-44962

Single-particle
4.1 Å
EMD-44962
3D View Gallery
Deposition: 21/05/2024
Map released: 25/06/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44962
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bw9 summary report (pdf.gz) Map and 9bw9 FULL report (pdf.gz)
EMICSS annotations (xml)

Tetrameric Complex of full-length HIV-1 integrase protein bound to the integrase binding domain of LEDGF/p75

EMD-44962

Single-particle
4.1 Å
EMD-44962
3D View Gallery
Deposition: 21/05/2024
Map released: 25/06/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: HIV type 1, Homo sapiens, HIV-1 06TG.HT008
Sample: Full-length tetrameric HIV-1 integrase bound to LEDGF IBD
Fitted models: 9bw9

Deposition Authors: Jing T, Shan Z, Lyumkis D, Biswas A
Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding.
Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D
(2025) Nat Commun , 16 , 9430 - 9430
PUBMED: 41136407
DOI: doi:10.1038/s41467-025-64479-8
ISSN: 2041-1723