Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

Edit your search query here and hit Return to execute it:
grant_code:"75N91019D00024"

Filter By

Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Complex [7]
  • Protein [7]
  • Ligand [4]

Organism

  • Homo sapiens [6]
  • Severe acute respiratory syndrome coronavirus [1]
  • Camelus dromedarius [1]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [4]

Release Date

  • 2025 [6]
  • 2022 [1]

Author by name

  • Bochtler M [6]
  • Czarnocki-cieciura M [6]
  • Gewartowska O [6]
  • Kanai T [6]
  • Lountos G [6]
  • Lountos GT [6]
  • Rathore I [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wang Z [6]
  • Wlodawer A [6]
  • Yang R [6]
  • Borgnia MJ [1]
  • Butay KJ [1]
  • Cachau R [1]
  • Chen CZ [1]
  • Dandey VP [1]
  • Esposito D [1]
  • Ho M [1]
  • Hong J [1]
  • Kwon HJ [1]
  • Martin N [1]
  • Ortega-rodriguez U [1]
  • Xie H [1]
  • Xu M [1]
  • Zhu J [1]

Author by ORCID

  • Czarnocki-cieciura M [6]
  • Bochtler M [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wlodawer A [6]
  • Lountos GT [6]

Journal

  • PNAS [6]
  • BIORXIV [1]

Software

  • CRYOSPARC [7]

Microscope

  • FEI TALOS ARCTICA [7]
  • FEI TITAN KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [7]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • UniProt [7]
  • AlphaFold DB [6]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • Pfam [5]
  • ChEBI [4]
  • ChEMBL [4]
  • DrugBank [4]
  • Complex Portal [1]
  • PDBe-Kb [1]
Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download
EMD-52121
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : trimer without a ligand
Release date: April 30, 2025
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 9hfq
Q-score: 0.638

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52122
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : hexamer without a ligand
Release date: April 30, 2025
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 9hfr
Q-score: 0.556

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52123
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : trimer in the presence of dCTP in solution not bound
Release date: April 30, 2025
Resolution: 3.08 Å
EM Method: Single-particle

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52124
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : hexamer with dCTP bound in the active site
Release date: April 30, 2025
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9hfs
Q-score: 0.689

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52125
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : trimer in the presence of 5mdCTP in solution not bound
Release date: April 30, 2025
Resolution: 2.81 Å
EM Method: Single-particle

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52126
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : hexamer with 5mdCTP bound in the active site
Release date: April 30, 2025
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9hft
Q-score: 0.665

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-26062
Download Map
3D View
Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants
Release date: April 20, 2022
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 7tpr
Q-score: 0.407

Hong J, Kwon HJ, Cachau R, Chen CZ, Dandey VP, Martin N, Esposito D, Ortega-Rodriguez U, Xu M, Borgnia MJ, Xie H, Ho M

bioRxiv (2021) [ DOI: doi:10.1101/2021.10.27.465996 Pubmed: 34751270 ]

Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Complex [7]
  • Protein [7]
  • Ligand [4]

Organism

  • Homo sapiens [6]
  • Severe acute respiratory syndrome coronavirus [1]
  • Camelus dromedarius [1]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [4]

Release Date

  • 2025 [6]
  • 2022 [1]

Author by name

  • Bochtler M [6]
  • Czarnocki-cieciura M [6]
  • Gewartowska O [6]
  • Kanai T [6]
  • Lountos G [6]
  • Lountos GT [6]
  • Rathore I [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wang Z [6]
  • Wlodawer A [6]
  • Yang R [6]
  • Borgnia MJ [1]
  • Butay KJ [1]
  • Cachau R [1]
  • Chen CZ [1]
  • Dandey VP [1]
  • Esposito D [1]
  • Ho M [1]
  • Hong J [1]
  • Kwon HJ [1]
  • Martin N [1]
  • Ortega-rodriguez U [1]
  • Xie H [1]
  • Xu M [1]
  • Zhu J [1]

Author by ORCID

  • Czarnocki-cieciura M [6]
  • Bochtler M [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wlodawer A [6]
  • Lountos GT [6]

Journal

  • PNAS [6]
  • BIORXIV [1]

Software

  • CRYOSPARC [7]

Microscope

  • FEI TALOS ARCTICA [7]
  • FEI TITAN KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [7]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • UniProt [7]
  • AlphaFold DB [6]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • Pfam [5]
  • ChEBI [4]
  • ChEMBL [4]
  • DrugBank [4]
  • Complex Portal [1]
  • PDBe-Kb [1]