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grant_code:"604718"

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Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [5]
  • Ligand [3]

Organism

  • Homo sapiens [5]
  • Lama glama [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 100-250 kDa [4]

Release Date

  • 2023 [1]
  • 2022 [4]

Author by name

  • De La O Becerra Ki [5]
  • Gros P [5]
  • Rooijakkers SHM [5]
  • Ruyken M [5]
  • Lorent JH [4]
  • Oosterheert W [4]
  • Schouten A [4]
  • Xenaki KT [4]
  • Van Bergen En Henegouwen Pmp [4]
  • Van Den Bos Rm [4]
  • Bardoel BW [1]
  • Dolk E [1]
  • Heesterbeek DAC [1]
  • Heukers R [1]
  • Siere DY [1]
  • Struijf EM [1]
  • De Haas Cjc [1]
  • Van Keulen Je [1]
  • Van Oosterom F [1]

Author by ORCID

  • Rooijakkers SHM [5]
  • Van Bergen En Henegouwen Pmp [4]
  • De La O Becerra Ki [4]
  • Xenaki KT [4]
  • Van Den Bos Rm [4]
  • Lorent JH [4]
  • Gros P [4]
  • Oosterheert W [4]
  • Ruyken M [4]
  • Struijf EM [1]
  • Heesterbeek DAC [1]
  • Van Keulen Je [1]

Journal

  • J IMMUNOL. [4]
  • J BIOL CHEM [1]

Software

  • RELION [4]
  • CRYOSPARC [1]
  • CTFFIND [1]

Microscope

  • FEI TALOS ARCTICA [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [5]

External links

  • AlphaFold DB [5]
  • PDBe-Kb [5]
  • UniProt [5]
  • Complex Portal [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • Pfam [4]
  • ChEBI [3]
  • ChEMBL [3]
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EMD-16730
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3D View
Cryo-EM structure of complement C5 in complex with nanobodies UNbC5-1 and UNbC5-2
Release date: Sept. 27, 2023
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8cml
Q-score: 0.415

Struijf EM, De la O Becerra KI, Ruyken M, de Haas CJC, van Oosterom F, Siere DY, van Keulen JE, Heesterbeek DAC, Dolk E, Heukers R, Bardoel BW, Gros P, Rooijakkers SHM

J Biol Chem (2023) 299 pp. 104956-104956 [ Pubmed: 37356719 DOI: doi:10.1016/j.jbc.2023.104956 ]

EMD-11988
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3D View
Cryo-EM structure of complement C4b in complex with nanobody E3
Release date: March 2, 2022
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 7b2m
Q-score: 0.445

De la O Becerra KI, Oosterheert W, van den Bos RM, Xenaki KT, Lorent JH, Ruyken M, Schouten A, Rooijakkers SHM, van Bergen En Henegouwen PMP, Gros P

J Immunol. (2022) 208 pp. 2207-2219 [ DOI: doi:10.4049/jimmunol.2100647 Pubmed: 35428691 ]

EMD-11989
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3D View
Cryo-EM structure of complement C4b in complex with nanobody B5
Release date: March 2, 2022
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 7b2p
Q-score: 0.411

De la O Becerra KI, Oosterheert W, van den Bos RM, Xenaki KT, Lorent JH, Ruyken M, Schouten A, Rooijakkers SHM, van Bergen En Henegouwen PMP, Gros P

J Immunol. (2022) 208 pp. 2207-2219 [ DOI: doi:10.4049/jimmunol.2100647 Pubmed: 35428691 ]

EMD-11990
Download Map
3D View
Cryo-EM structure of complement C4b in complex with nanobody B12
Release date: March 2, 2022
Resolution: 3.76 Å
EM Method: Single-particle
Fitted PDBs: 7b2q
Q-score: 0.371

De la O Becerra KI, Oosterheert W, van den Bos RM, Xenaki KT, Lorent JH, Ruyken M, Schouten A, Rooijakkers SHM, van Bergen En Henegouwen PMP, Gros P

J Immunol. (2022) 208 pp. 2207-2219 [ DOI: doi:10.4049/jimmunol.2100647 Pubmed: 35428691 ]

EMD-11991
Download Map
3D View
Cryo-EM density map of complement C4b in complex with nanobody G3
Release date: Jan. 12, 2022
Resolution: 3.96 Å
EM Method: Single-particle

De la O Becerra KI, Oosterheert W, van den Bos RM, Xenaki KT, Lorent JH, Ruyken M, Schouten A, Rooijakkers SHM, van Bergen En Henegouwen PMP, Gros P

J Immunol. (2022) 208 pp. 2207-2219 [ DOI: doi:10.4049/jimmunol.2100647 Pubmed: 35428691 ]

Sort by: Download
Showing 1 - 5 of 5. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [5]
  • Ligand [3]

Organism

  • Homo sapiens [5]
  • Lama glama [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 100-250 kDa [4]

Release Date

  • 2023 [1]
  • 2022 [4]

Author by name

  • De La O Becerra Ki [5]
  • Gros P [5]
  • Rooijakkers SHM [5]
  • Ruyken M [5]
  • Lorent JH [4]
  • Oosterheert W [4]
  • Schouten A [4]
  • Xenaki KT [4]
  • Van Bergen En Henegouwen Pmp [4]
  • Van Den Bos Rm [4]
  • Bardoel BW [1]
  • Dolk E [1]
  • Heesterbeek DAC [1]
  • Heukers R [1]
  • Siere DY [1]
  • Struijf EM [1]
  • De Haas Cjc [1]
  • Van Keulen Je [1]
  • Van Oosterom F [1]

Author by ORCID

  • Rooijakkers SHM [5]
  • Van Bergen En Henegouwen Pmp [4]
  • De La O Becerra Ki [4]
  • Xenaki KT [4]
  • Van Den Bos Rm [4]
  • Lorent JH [4]
  • Gros P [4]
  • Oosterheert W [4]
  • Ruyken M [4]
  • Struijf EM [1]
  • Heesterbeek DAC [1]
  • Van Keulen Je [1]

Journal

  • J IMMUNOL. [4]
  • J BIOL CHEM [1]

Software

  • RELION [4]
  • CRYOSPARC [1]
  • CTFFIND [1]

Microscope

  • FEI TALOS ARCTICA [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [5]

External links

  • AlphaFold DB [5]
  • PDBe-Kb [5]
  • UniProt [5]
  • Complex Portal [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • Pfam [4]
  • ChEBI [3]
  • ChEMBL [3]