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EMD-16730

Single-particle
3.6 Å
EMD-16730
3D View Gallery
Deposition: 20/02/2023
Map released: 27/09/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16730
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8cml summary report (pdf.gz) Map and 8cml FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of complement C5 in complex with nanobodies UNbC5-1 and UNbC5-2

EMD-16730

Single-particle
3.6 Å
EMD-16730
3D View Gallery
Deposition: 20/02/2023
Map released: 27/09/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Complement C5 bound to nanobodies UNbC5-1 and UNbC5-2
Fitted models: 8cml

Deposition Authors: De la O Becerra KI, Gros P
Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies.
Struijf EM , De la O Becerra KI, Ruyken M, de Haas CJC, van Oosterom F, Siere DY, van Keulen JE , Heesterbeek DAC , Dolk E, Heukers R, Bardoel BW, Gros P, Rooijakkers SHM
(2023) J Biol Chem , 299 , 104956 - 104956
PUBMED: 37356719
DOI: doi:10.1016/j.jbc.2023.104956
ISSN: 1083-351X
ASTM: JBCHA3