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grant_code:"21625201"

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Current Database

  • EMDB [10]

Current status

  • REL [10]

Sample type

  • Complex [10]
  • Ligand [10]
  • Protein [10]

Organism

  • Homo sapiens [10]
  • Synthetic construct [5]
  • Pseudotevenvirus rb43 [1]

EM Method

  • Single-particle [10]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [6]

Model molecular weight

  • 250-500 kDa [4]
  • 500-1000 kDa [6]

Release Date

  • 2024 [6]
  • 2022 [4]

Author by name

  • Fan J [10]
  • Ke H [10]
  • Lei X [10]
  • Liao D [8]
  • Lei J [6]
  • Tominaga M [6]
  • Guo C [4]
  • Guo F [4]
  • Hu L [4]
  • Huang Z [4]
  • Jiang D [4]
  • Tang Y [4]
  • Xie W [4]
  • Yang Y [4]
  • Yue Z [4]
  • Wang J [2]

Author by ORCID

  • Lei X [10]
  • Fan J [10]
  • Lei J [6]
  • Tominaga M [6]
  • Huang Z [4]
  • Jiang D [4]
  • Yang Y [4]
  • Hu L [4]
  • Ke H [4]
  • Xie W [4]
  • Tang Y [4]
  • Liao D [4]
  • Guo C [4]

Journal

  • ADV SCI [4]
  • NAT CHEM BIOL [4]
  • NAT COMMUN [2]

Microscope

  • FEI TITAN KRIOS [10]

Electron Source

  • FIELD EMISSION GUN [10]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [8]
  • GATAN K3 6K X 4K [2]

External links

  • AlphaFold DB [10]
  • PDB [10]
  • UniProt [10]
  • Gene Ontology [6]
  • InterPro [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • ChEBI [5]
  • ChEMBL [3]
  • DrugBank [3]
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EMD-36577
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Structure of human TRPV1 in complex with antagonist
Release date: Aug. 14, 2024
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8jqr
Q-score: 0.549

Fan J, Ke H, Lei J, Wang J, Tominaga M, Lei X

Nat Commun (2024) 15 pp. 6689-6689 [ Pubmed: 39107321 DOI: doi:10.1038/s41467-024-51085-3 ]

EMD-38161
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Structure of human TRPV1 in complex with antagonist --protein purified without CHS
Release date: Aug. 14, 2024
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8x94
Q-score: 0.536

Fan J, Ke H, Lei J, Wang J, Tominaga M, Lei X

Nat Commun (2024) 15 pp. 6689-6689 [ Pubmed: 39107321 DOI: doi:10.1038/s41467-024-51085-3 ]

EMD-36659
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Structure of human TRPV4 with antagonist A1
Release date: May 8, 2024
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 8ju5
Q-score: 0.374

Fan J, Guo C, Liao D, Ke H, Lei J, Xie W, Tang Y, Tominaga M, Huang Z, Lei X

Adv Sci (2024) 11 pp. e2401583-e2401583 [ DOI: doi:10.1002/advs.202401583 Pubmed: 38659239 ]

EMD-36660
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Structure of human TRPV4 with antagonist GSK279
Release date: May 8, 2024
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8ju6
Q-score: 0.415

Fan J, Guo C, Liao D, Ke H, Lei J, Xie W, Tang Y, Tominaga M, Huang Z, Lei X

Adv Sci (2024) 11 pp. e2401583-e2401583 [ DOI: doi:10.1002/advs.202401583 Pubmed: 38659239 ]

EMD-36675
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Structure of human TRPV4 with antagonist A2
Release date: May 8, 2024
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8jvi
Q-score: 0.418

Fan J, Guo C, Liao D, Ke H, Lei J, Xie W, Tang Y, Tominaga M, Huang Z, Lei X

Adv Sci (2024) 11 pp. e2401583-e2401583 [ DOI: doi:10.1002/advs.202401583 Pubmed: 38659239 ]

EMD-36676
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Structure of human TRPV4 with antagonist A2 and RhoA
Release date: May 8, 2024
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 8jvj
Q-score: 0.378

Fan J, Guo C, Liao D, Ke H, Lei J, Xie W, Tang Y, Tominaga M, Huang Z, Lei X

Adv Sci (2024) 11 pp. e2401583-e2401583 [ DOI: doi:10.1002/advs.202401583 Pubmed: 38659239 ]

EMD-33214
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Structure of human TRPV3 in complex with Trpvicin
Release date: Nov. 9, 2022
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 7xj0
Q-score: 0.576

Fan J, Hu L, Yue Z, Liao D, Guo F, Ke H, Jiang D, Yang Y, Lei X

Nat Chem Biol (2023) 19 pp. 81-90 [ DOI: doi:10.1038/s41589-022-01166-5 Pubmed: 36302896 ]

EMD-33216
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Structure of human TRPV3_G573S in complex with Trpvicin in C2 symmetry
Release date: Nov. 9, 2022
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 7xj1
Q-score: 0.563

Fan J, Hu L, Yue Z, Liao D, Guo F, Ke H, Jiang D, Yang Y, Lei X

Nat Chem Biol (2023) 19 pp. 81-90 [ DOI: doi:10.1038/s41589-022-01166-5 Pubmed: 36302896 ]

EMD-33217
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3D View
Structure of human TRPV3_G573S in complex with Trpvicin in C4 symmetry
Release date: Nov. 9, 2022
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 7xj2
Q-score: 0.447

Fan J, Hu L, Yue Z, Liao D, Guo F, Ke H, Jiang D, Yang Y, Lei X

Nat Chem Biol (2023) 19 pp. 81-90 [ DOI: doi:10.1038/s41589-022-01166-5 Pubmed: 36302896 ]

EMD-33218
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3D View
Structure of human TRPV3
Release date: Nov. 9, 2022
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 7xj3
Q-score: 0.521

Fan J, Hu L, Yue Z, Liao D, Guo F, Ke H, Jiang D, Yang Y, Lei X

Nat Chem Biol (2023) 19 pp. 81-90 [ DOI: doi:10.1038/s41589-022-01166-5 Pubmed: 36302896 ]

Sort by: Download
Showing 1 - 10 of 10. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [10]

Current status

  • REL [10]

Sample type

  • Complex [10]
  • Ligand [10]
  • Protein [10]

Organism

  • Homo sapiens [10]
  • Synthetic construct [5]
  • Pseudotevenvirus rb43 [1]

EM Method

  • Single-particle [10]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [6]

Model molecular weight

  • 250-500 kDa [4]
  • 500-1000 kDa [6]

Release Date

  • 2024 [6]
  • 2022 [4]

Author by name

  • Fan J [10]
  • Ke H [10]
  • Lei X [10]
  • Liao D [8]
  • Lei J [6]
  • Tominaga M [6]
  • Guo C [4]
  • Guo F [4]
  • Hu L [4]
  • Huang Z [4]
  • Jiang D [4]
  • Tang Y [4]
  • Xie W [4]
  • Yang Y [4]
  • Yue Z [4]
  • Wang J [2]

Author by ORCID

  • Lei X [10]
  • Fan J [10]
  • Lei J [6]
  • Tominaga M [6]
  • Huang Z [4]
  • Jiang D [4]
  • Yang Y [4]
  • Hu L [4]
  • Ke H [4]
  • Xie W [4]
  • Tang Y [4]
  • Liao D [4]
  • Guo C [4]

Journal

  • ADV SCI [4]
  • NAT CHEM BIOL [4]
  • NAT COMMUN [2]

Microscope

  • FEI TITAN KRIOS [10]

Electron Source

  • FIELD EMISSION GUN [10]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [8]
  • GATAN K3 6K X 4K [2]

External links

  • AlphaFold DB [10]
  • PDB [10]
  • UniProt [10]
  • Gene Ontology [6]
  • InterPro [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • ChEBI [5]
  • ChEMBL [3]
  • DrugBank [3]