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grant_code:"1DP2HL163810-01"

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Current Database

  • EMDB [15]

Current status

  • REL [15]

Sample type

  • Protein [14]
  • Tissue [13]
  • Complex [2]
  • Other [1]

Organism

  • Homo sapiens [15]

EM Method

  • Helical reconstruction [15]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 50-100 kDa [14]

Release Date

  • 2025 [8]
  • 2024 [2]
  • 2023 [5]

Author by name

  • Nguyen BA [15]
  • Saelices L [15]
  • Afrin S [14]
  • Pedretti R [14]
  • Pekala M [14]
  • Singh V [14]
  • Ahmed Y [12]
  • Singh P [12]
  • Canepa J [10]
  • Wang L [10]
  • Bassett P [8]
  • Cabrera Hernandez Lo [8]
  • Fernandez-ramirez MDC [8]
  • Lemoff A [8]
  • Nguyen AB [8]
  • Boyer DR [6]
  • Cao Q [6]
  • Escobar CL [6]
  • Evers B [6]
  • Fernandez-ramirez MC [6]
  • Kluve-beckerman B [6]
  • Li Y [6]
  • Shelton JM [6]
  • Wosztyl A [6]
  • Chhapra F [4]
  • Wydorski PM [4]
  • Yakubovska A [4]
  • Alicea JV [2]
  • Benson MD [2]
  • Eisenberg DS [2]
  • Gonzalez-prieto R [2]
  • Kumar S [2]
  • Kunach P [2]
  • Sawaya MR [2]

Author by ORCID

  • Lemoff A [5]
  • Nguyen BA [3]
  • Saelices L [3]
  • Singh V [3]
  • Singh P [3]
  • Wydorski PM [2]
  • Afrin S [2]
  • Bassett P [2]
  • Gonzalez-prieto R [1]
  • Sawaya MR [1]
  • Eisenberg DS [1]
  • Cabrera Hernandez Lo [1]

Journal

  • STRUCTURE [8]
  • COMMUN BIOL [4]
  • NAT COMMUN [2]
  • TO BE PUBLISHED [1]

Software

  • RELION [15]
  • TOPAZ [5]
  • EMAN2 [1]

Microscope

  • FEI TITAN KRIOS [15]

Electron Source

  • FIELD EMISSION GUN [15]

Film or detector model

  • GATAN K3 6K X 4K [11]
  • FEI FALCON IV 4K X 4K [4]

External links

  • AlphaFold DB [14]
  • PDB [14]
  • PDBe-Kb [14]
  • UniProt [14]
  • Pfam [13]
  • InterPro [8]
  • Gene Ontology [7]
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Showing 1 - 10 of 15. Page 1 of 2
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EMD-46479
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3D View
Cryo-EM structure of amyloid fibril extracted from heart of a variant ATTR T60A amyloidosis patient 1
Release date: Aug. 13, 2025
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 9d21
Q-score: 0.491

Fernandez-Ramirez MDC, Nguyen BA, Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L

Structure (2025) 33 pp. 2013-2019.e4 [ Pubmed: 41106377 DOI: doi:10.1016/j.str.2025.09.008 ]

EMD-46481
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3D View
Cryo-EM structure of amyloid fibril extracted from heart of a variant ATTR T60A amyloidosis patient 2
Release date: Aug. 13, 2025
Resolution: 3.18 Å
EM Method: Helical reconstruction
Fitted PDBs: 9d23
Q-score: 0.578

Fernandez-Ramirez MDC, Nguyen BA, Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L

Structure (2025) 33 pp. 2013-2019.e4 [ Pubmed: 41106377 DOI: doi:10.1016/j.str.2025.09.008 ]

EMD-46482
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3D View
Cryo-EM structure of amyloid fibril extracted from thyroid of a variant ATTR T60A amyloidosis patient 3
Release date: Aug. 13, 2025
Resolution: 2.98 Å
EM Method: Helical reconstruction
Fitted PDBs: 9d24
Q-score: 0.552

Fernandez-Ramirez MDC, Nguyen BA, Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L

Structure (2025) 33 pp. 2013-2019.e4 [ Pubmed: 41106377 DOI: doi:10.1016/j.str.2025.09.008 ]

EMD-46487
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3D View
Cryo-EM structure of amyloid fibril extracted from kidney of a variant ATTR T60A amyloidosis patient 3
Release date: Aug. 13, 2025
Resolution: 3.19 Å
EM Method: Helical reconstruction
Fitted PDBs: 9d27
Q-score: 0.533

Fernandez-Ramirez MDC, Nguyen BA, Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L

Structure (2025) 33 pp. 2013-2019.e4 [ Pubmed: 41106377 DOI: doi:10.1016/j.str.2025.09.008 ]

EMD-46495
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3D View
Cryo-EM structure of amyloid fibril extracted from liver of a variant ATTR T60A amyloidosis patient 3
Release date: Aug. 13, 2025
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 9d2g
Q-score: 0.56

Fernandez-Ramirez MDC, Nguyen BA, Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L

Structure (2025) 33 pp. 2013-2019.e4 [ Pubmed: 41106377 DOI: doi:10.1016/j.str.2025.09.008 ]

EMD-46496
Download Map
3D View
Cryo-EM structure of amyloid fibril extracted from heart of a variant ATTR T60A amyloidosis patient 3
Release date: Aug. 13, 2025
Resolution: 4.64 Å
EM Method: Helical reconstruction

Fernandez-Ramirez MDC, Nguyen BA, Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L

Structure (2025) 33 pp. 2013-2019.e4 [ Pubmed: 41106377 DOI: doi:10.1016/j.str.2025.09.008 ]

EMD-45039
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3D View
Cryo-EM structure of amyloid fibril extracted from nerve of a variant ATTR V30M amyloidosis patient
Release date: March 12, 2025
Resolution: 3.36 Å
EM Method: Helical reconstruction
Fitted PDBs: 9byn
Q-score: 0.555

Nguyen BA, Afrin S, Yakubovska A, Singh V, Pedretti R, Bassett P, Pekala M, Alicea JV, Kunach P, Wang L, Lemoff A, Kluve-Beckerman B, Saelices L

Structure (2024) 32 pp. 2244-2250.e3 [ DOI: doi:10.1016/j.str.2024.09.021 Pubmed: 39423808 ]

EMD-45074
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Cryo-EM structure of cardiac amyloid fibril from a variant ATTR V30M amyloidosis patient
Release date: March 12, 2025
Resolution: 3.14 Å
EM Method: Helical reconstruction
Fitted PDBs: 9bzs
Q-score: 0.587

Nguyen BA, Afrin S, Yakubovska A, Singh V, Pedretti R, Bassett P, Pekala M, Alicea JV, Kunach P, Wang L, Lemoff A, Kluve-Beckerman B, Saelices L

Structure (2024) 32 pp. 2244-2250.e3 [ DOI: doi:10.1016/j.str.2024.09.021 Pubmed: 39423808 ]

EMD-29920
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3D View
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Release date: Feb. 28, 2024
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8gbr
Q-score: 0.513

Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L

Commun Biol (2024) 7 pp. 905-905 [ Pubmed: 39068302 DOI: doi:10.1038/s42003-024-06588-6 ]

EMD-29874
Download Map
3D View
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
Release date: Feb. 21, 2024
Resolution: 3.28 Å
EM Method: Helical reconstruction
Fitted PDBs: 8g9r
Q-score: 0.038

Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L

Commun Biol (2024) 7 pp. 905-905 [ Pubmed: 39068302 DOI: doi:10.1038/s42003-024-06588-6 ]

Sort by: Download
Showing 1 - 10 of 15. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [15]

Current status

  • REL [15]

Sample type

  • Protein [14]
  • Tissue [13]
  • Complex [2]
  • Other [1]

Organism

  • Homo sapiens [15]

EM Method

  • Helical reconstruction [15]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 50-100 kDa [14]

Release Date

  • 2025 [8]
  • 2024 [2]
  • 2023 [5]

Author by name

  • Nguyen BA [15]
  • Saelices L [15]
  • Afrin S [14]
  • Pedretti R [14]
  • Pekala M [14]
  • Singh V [14]
  • Ahmed Y [12]
  • Singh P [12]
  • Canepa J [10]
  • Wang L [10]
  • Bassett P [8]
  • Cabrera Hernandez Lo [8]
  • Fernandez-ramirez MDC [8]
  • Lemoff A [8]
  • Nguyen AB [8]
  • Boyer DR [6]
  • Cao Q [6]
  • Escobar CL [6]
  • Evers B [6]
  • Fernandez-ramirez MC [6]
  • Kluve-beckerman B [6]
  • Li Y [6]
  • Shelton JM [6]
  • Wosztyl A [6]
  • Chhapra F [4]
  • Wydorski PM [4]
  • Yakubovska A [4]
  • Alicea JV [2]
  • Benson MD [2]
  • Eisenberg DS [2]
  • Gonzalez-prieto R [2]
  • Kumar S [2]
  • Kunach P [2]
  • Sawaya MR [2]

Author by ORCID

  • Lemoff A [5]
  • Nguyen BA [3]
  • Saelices L [3]
  • Singh V [3]
  • Singh P [3]
  • Wydorski PM [2]
  • Afrin S [2]
  • Bassett P [2]
  • Gonzalez-prieto R [1]
  • Sawaya MR [1]
  • Eisenberg DS [1]
  • Cabrera Hernandez Lo [1]

Journal

  • STRUCTURE [8]
  • COMMUN BIOL [4]
  • NAT COMMUN [2]
  • TO BE PUBLISHED [1]

Software

  • RELION [15]
  • TOPAZ [5]
  • EMAN2 [1]

Microscope

  • FEI TITAN KRIOS [15]

Electron Source

  • FIELD EMISSION GUN [15]

Film or detector model

  • GATAN K3 6K X 4K [11]
  • FEI FALCON IV 4K X 4K [4]

External links

  • AlphaFold DB [14]
  • PDB [14]
  • PDBe-Kb [14]
  • UniProt [14]
  • Pfam [13]
  • InterPro [8]
  • Gene Ontology [7]