EMD-46487

Helical reconstruction
3.19 Å
EMD-46487
3D View Gallery
Deposition: 08/08/2024
Map released: 13/08/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46487

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9d27 summary report (pdf.gz) Map-9d27 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of amyloid fibril extracted from kidney of a variant ATTR T60A amyloidosis patient 3

EMD-46487

Helical reconstruction
3.19 Å
EMD-46487
3D View Gallery
Deposition: 08/08/2024
Map released: 13/08/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Amyloid fibril from kidney of a variant ATTR T60A amyloidosis patient
Fitted models: 9d27

Deposition Authors: Nguyen AB , Fernandez-Ramirez MC , Saelices L
Structural and molecular homogeneity of ATTRv-T60A amyloid fibrils across patients and organs.
Fernandez-Ramirez MDC, Nguyen BA, Afrin S, Singh V, Evers B, Shelton JM, Escobar CL, Bassett P, Wang L, Pekala M, Ahmed Y, Cabrera Hernandez LO, Pedretti R, Singh P, Canepa J, Wosztyl A, Li Y, Boyer DR, Cao Q, Saelices L
(2025) Structure , 33 , 2013 - 2019.e4
PUBMED: 41106377
DOI: doi:10.1016/j.str.2025.09.008
ISSN: 0969-2126
ASTM: STRUE6