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grant_code:"12S0519N"

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Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Mus musculus [6]
  • Homo sapiens [1]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [3]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [4]

Release Date

  • 2024 [6]

Author by name

  • Bloch Y [6]
  • De Backer R [6]
  • Felix J [6]
  • Lambert E [6]
  • Mehdipour AR [6]
  • Merceron R [6]
  • Provost M [6]
  • Savvides SN [6]
  • Symakani RA [6]

Author by ORCID

  • Bloch Y [6]
  • Symakani RA [6]
  • Felix J [6]
  • Savvides SN [6]
  • De Backer R [6]

Journal

  • NAT STRUCT MOL BIOL [6]

Software

  • CRYOSPARC [5]

Microscope

  • JEOL CRYO ARM 300 [6]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 6K X 4K [6]

External links

  • AlphaFold DB [6]
  • Complex Portal [6]
  • PDBe-Kb [6]
  • UniProt [6]
  • ChEBI [4]
  • ChEMBL [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • Pfam [4]
  • DrugBank [2]
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Showing 1 - 6 of 6. Page 1 of 1
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EMD-16820
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3D View
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex Class 1 .
Release date: Feb. 7, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8odz
Q-score: 0.329

Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN

Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]

EMD-16821
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3D View
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex Class 2 .
Release date: Feb. 7, 2024
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 8oe0
Q-score: 0.208

Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN

Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]

EMD-16822
Download Map
3D View
Cryo-EM structure of the murine IL-12 complete extracellular signaling complex Class 1 .
Release date: Feb. 7, 2024
Resolution: 5.6 Å
EM Method: Single-particle

Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN

Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]

EMD-16823
Download Map
3D View
Cryo-EM structure of the murine IL-12 complete extracellular signaling complex Class 2 .
Release date: Feb. 7, 2024
Resolution: 6.7 Å
EM Method: Single-particle

Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN

Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]

EMD-16824
Download Map
3D View
Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex.
Release date: Feb. 7, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8oe4
Q-score: 0.294

Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN

Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]

EMD-17580
Download Map
3D View
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex Class 1 , obtained after local refinement.
Release date: Feb. 7, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8pb1
Q-score: 0.424

Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN

Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]

Sort by: Download
Showing 1 - 6 of 6. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Mus musculus [6]
  • Homo sapiens [1]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [3]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [4]

Release Date

  • 2024 [6]

Author by name

  • Bloch Y [6]
  • De Backer R [6]
  • Felix J [6]
  • Lambert E [6]
  • Mehdipour AR [6]
  • Merceron R [6]
  • Provost M [6]
  • Savvides SN [6]
  • Symakani RA [6]

Author by ORCID

  • Bloch Y [6]
  • Symakani RA [6]
  • Felix J [6]
  • Savvides SN [6]
  • De Backer R [6]

Journal

  • NAT STRUCT MOL BIOL [6]

Software

  • CRYOSPARC [5]

Microscope

  • JEOL CRYO ARM 300 [6]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 6K X 4K [6]

External links

  • AlphaFold DB [6]
  • Complex Portal [6]
  • PDBe-Kb [6]
  • UniProt [6]
  • ChEBI [4]
  • ChEMBL [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • Pfam [4]
  • DrugBank [2]