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grant_code:"101020432-MeChroRep"

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Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [8]
  • DNA [7]
  • Ligand [7]
  • Protein [7]

Organism

  • Homo sapiens [8]
  • Synthetic construct [7]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 3Å and < 4Å [5]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]

Model molecular weight

  • 250-500 kDa [1]
  • 500-1000 kDa [4]
  • 1-2 MDa [2]

Release Date

  • 2024 [8]

Author by name

  • Costa A [8]
  • Couves EC [8]
  • Diffley JFX [8]
  • Eastwood EL [8]
  • Greiwe JF [8]
  • Miller TCR [8]
  • Puhringer T [8]
  • Weissmann F [8]
  • Greiwe J [1]
  • Puehringer T [1]

Author by ORCID

  • Diffley JFX [8]
  • Puhringer T [8]
  • Eastwood EL [8]
  • Weissmann F [8]
  • Greiwe JF [8]
  • Miller TCR [8]
  • Costa A [8]
  • Couves EC [8]

Journal

  • ACTA CRYSTALLOGR D STRUCT BIOL [8]
  • BIORXIV [8]
  • NATURE [8]

Software

  • CRYOSPARC [5]

Microscope

  • FEI TITAN KRIOS [7]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [7]
  • FEI FALCON III 4K X 4K [1]

External links

  • AlphaFold DB [7]
  • ChEBI [7]
  • ChEMBL [7]
  • DrugBank [7]
  • Gene Ontology [7]
  • InterPro [7]
  • PDB [7]
  • PDBe-Kb [7]
  • Pfam [7]
  • UniProt [7]
  • Complex Portal [6]
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EMD-19618
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3D View
H. sapiens MCM2-7 double hexamer bound to double stranded DNA
Release date: Oct. 2, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8s09
Q-score: 0.448

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

EMD-19619
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3D View
H. sapiens MCM2-7 hexamer bound to double stranded DNA
Release date: Oct. 2, 2024
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8s0a
Q-score: 0.442

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

EMD-19620
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H. sapiens MCM bound to double stranded DNA and ORC6 as part of the MCM-ORC complex
Release date: Oct. 2, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8s0b
Q-score: 0.377

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

EMD-19621
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H. sapiens ORC1-5 bound to double stranded DNA as part of the MCM-ORC complex
Release date: Oct. 2, 2024
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8s0c
Q-score: 0.289

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

EMD-19622
Composite map
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H. sapiens MCM bound to double stranded DNA and ORC1-6
Release date: Oct. 2, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8s0d
Q-score: 0.346

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

EMD-19623
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H. sapiens OCCM bound to double stranded DNA
Release date: Oct. 2, 2024
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8s0e
Q-score: 0.24

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

EMD-19624
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H. sapiens OC1M bound to double stranded DNA
Release date: Oct. 2, 2024
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8s0f
Q-score: 0.212

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

EMD-19625
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3D View
H. sapiens MCM double hexamer containing the MCM5 R195A/L209G mutant
Release date: Oct. 2, 2024
Resolution: 5.6 Å
EM Method: Single-particle

Weissmann F, Greiwe JF, Puhringer T, Eastwood EL, Couves EC, Miller TCR, Diffley JFX, Costa A

Nature (2024) 636 pp. 499-508 [ DOI: doi:10.1038/s41586-024-08263-6 Pubmed: 39604733 ]

Sort by: Download
Showing 1 - 8 of 8. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [8]
  • DNA [7]
  • Ligand [7]
  • Protein [7]

Organism

  • Homo sapiens [8]
  • Synthetic construct [7]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 3Å and < 4Å [5]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]

Model molecular weight

  • 250-500 kDa [1]
  • 500-1000 kDa [4]
  • 1-2 MDa [2]

Release Date

  • 2024 [8]

Author by name

  • Costa A [8]
  • Couves EC [8]
  • Diffley JFX [8]
  • Eastwood EL [8]
  • Greiwe JF [8]
  • Miller TCR [8]
  • Puhringer T [8]
  • Weissmann F [8]
  • Greiwe J [1]
  • Puehringer T [1]

Author by ORCID

  • Diffley JFX [8]
  • Puhringer T [8]
  • Eastwood EL [8]
  • Weissmann F [8]
  • Greiwe JF [8]
  • Miller TCR [8]
  • Costa A [8]
  • Couves EC [8]

Journal

  • ACTA CRYSTALLOGR D STRUCT BIOL [8]
  • BIORXIV [8]
  • NATURE [8]

Software

  • CRYOSPARC [5]

Microscope

  • FEI TITAN KRIOS [7]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [7]
  • FEI FALCON III 4K X 4K [1]

External links

  • AlphaFold DB [7]
  • ChEBI [7]
  • ChEMBL [7]
  • DrugBank [7]
  • Gene Ontology [7]
  • InterPro [7]
  • PDB [7]
  • PDBe-Kb [7]
  • Pfam [7]
  • UniProt [7]
  • Complex Portal [6]