Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-19620

Single-particle
3.6 Å
EMD-19620 Deposition: 13/02/2024
Map released: 02/10/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19620

H. sapiens MCM bound to double stranded DNA and ORC6 as part of the MCM-ORC complex

EMD-19620

Single-particle
3.6 Å
EMD-19620 Deposition: 13/02/2024
Map released: 02/10/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: H. sapiens MCM bound to double stranded DNA and ORC6 as part of the MCM-ORC complex
Fitted models: 8s0b

Deposition Authors: Greiwe JF , Weissmann F , Diffley JFX , Costa A
MCM double hexamer loading visualized with human proteins.
Weissmann F , Greiwe JF , Puhringer T , Eastwood EL , Couves EC , Miller TCR , Diffley JFX , Costa A
(2024) Nature , 636 , 499 - 508
PUBMED: 39604733
DOI: doi:10.1038/s41586-024-08263-6
ISSN: 1476-4687
ASTM: NATUAS