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author:"Loria PM"

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Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [5]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 0-50 kDa [1]
  • 100-250 kDa [1]
  • 250-500 kDa [4]

Release Date

  • 2026 [1]
  • 2022 [5]

Author by name

  • Han S [6]
  • Loria PM [6]
  • Berg AP [4]
  • Ferreira IM [4]
  • Froese DS [4]
  • Mccorvie TJ [4]
  • Shrestha L [4]
  • Tu M [4]
  • Yue WW [4]
  • Bagley SW [1]
  • Buckeridge C [1]
  • Corpina RA [1]
  • Craig T [1]
  • Curto JM [1]
  • Derksen DR [1]
  • Dias JM [1]
  • Edmonds DJ [1]
  • Fennell K [1]
  • Fortin JP [1]
  • Griffith DA [1]
  • Griffor MC [1]
  • Healy DR [1]
  • Huang Z [1]
  • Huynh KW [1]
  • Jackson VM [1]
  • Jove V [1]
  • Kalgutkar AS [1]
  • Kuzmiski JB [1]
  • Landis MS [1]
  • Lee CW [1]
  • Lettiere D [1]
  • Levine K [1]
  • Limberakis C [1]
  • Liu Y [1]
  • Mathiowetz AM [1]
  • Patel JC [1]
  • Piotrowski DW [1]
  • Plumb R [1]
  • Price DA [1]
  • Ralph EC [1]
  • Ruggeri RB [1]
  • Saxena AR [1]
  • Schenone M [1]
  • Tess DA [1]
  • Wang F [1]
  • Wes PD [1]
  • Wheeler H [1]
  • Wu H [1]
  • Yamaguchi M [1]

Author by ORCID

  • Yue WW [4]
  • Han S [4]
  • Mccorvie TJ [4]
  • Froese DS [4]
  • Berg AP [4]
  • Kalgutkar AS [1]
  • Ruggeri RB [1]
  • Piotrowski DW [1]
  • Bagley SW [1]
  • Griffith DA [1]
  • Limberakis C [1]

Journal

  • NAT STRUCT MOL BIOL [4]
  • BIORXIV [1]
  • J MED CHEM [1]

Software

  • RELION [5]
  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [5]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 6K X 4K [4]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • AlphaFold DB [6]
  • Gene Ontology [6]
  • InterPro [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Complex Portal [4]
  • ChEBI [3]
  • DrugBank [3]
  • ChEMBL [2]
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EMD-74146
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Cryo-EM Structure of Human STAT2-USP18-ISG15 Complex
CryoEM
Release date: March 18, 2026
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 9zfo
Q-score: 0.469

Huynh KW, Plumb R, Healy DR, Jove V, Ralph EC, Lee CW, Wheeler H, Levine K, Huang Z, Fennell K, Corpina RA, Craig T, Wes PD, Loria PM, Schenone M, Han S, Wang F, Wu H, Yamaguchi M

bioRxiv (2026) [ DOI: doi:10.64898/2026.02.12.705587 ]

EMD-13743
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Human GYS1-GYG1 complex inhibited state
CryoEM
Release date: July 27, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7q0b
Q-score: 0.569

McCorvie TJ, Loria PM, Tu M, Han S, Shrestha L, Froese DS, Ferreira IM, Berg AP, Yue WW

Nat Struct Mol Biol (2022) 29 pp. 628-638 [ DOI: doi:10.1038/s41594-022-00799-3 Pubmed: 35835870 ]

EMD-13751
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3D View
Human GYS1-GYG1 complex inhibited-like state bound to glucose-6-phosphate
CryoEM
Release date: July 27, 2022
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7q0s
Q-score: 0.375

McCorvie TJ, Loria PM, Tu M, Han S, Shrestha L, Froese DS, Ferreira IM, Berg AP, Yue WW

Nat Struct Mol Biol (2022) 29 pp. 628-638 [ DOI: doi:10.1038/s41594-022-00799-3 Pubmed: 35835870 ]

EMD-13752
Download Map
3D View
Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate
CryoEM
Release date: July 27, 2022
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7q12
Q-score: 0.377

McCorvie TJ, Loria PM, Tu M, Han S, Shrestha L, Froese DS, Ferreira IM, Berg AP, Yue WW

Nat Struct Mol Biol (2022) 29 pp. 628-638 [ DOI: doi:10.1038/s41594-022-00799-3 Pubmed: 35835870 ]

EMD-13753
Download Map
3D View
Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate, uridine diphosphate, and glucose
CryoEM
Release date: July 27, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7q13
Q-score: 0.435

McCorvie TJ, Loria PM, Tu M, Han S, Shrestha L, Froese DS, Ferreira IM, Berg AP, Yue WW

Nat Struct Mol Biol (2022) 29 pp. 628-638 [ DOI: doi:10.1038/s41594-022-00799-3 Pubmed: 35835870 ]

EMD-24794
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3D View
GLP-1 receptor bound with Pfizer small molecule agonist
CryoEM
Release date: June 8, 2022
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7s15
Q-score: 0.405

Griffith DA, Edmonds DJ, Fortin JP, Kalgutkar AS, Kuzmiski JB, Loria PM, Saxena AR, Bagley SW, Buckeridge C, Curto JM, Derksen DR, Dias JM, Griffor MC, Han S, Jackson VM, Landis MS, Lettiere D, Limberakis C, Liu Y, Mathiowetz AM, Patel JC, Piotrowski DW, Price DA, Ruggeri RB, Tess DA

J Med Chem (2022) 65 pp. 8208-8226 [ Pubmed: 35647711 DOI: doi:10.1021/acs.jmedchem.1c01856 ]

Sort by: Download
Showing 1 - 6 of 6. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [5]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 0-50 kDa [1]
  • 100-250 kDa [1]
  • 250-500 kDa [4]

Release Date

  • 2026 [1]
  • 2022 [5]

Author by name

  • Han S [6]
  • Loria PM [6]
  • Berg AP [4]
  • Ferreira IM [4]
  • Froese DS [4]
  • Mccorvie TJ [4]
  • Shrestha L [4]
  • Tu M [4]
  • Yue WW [4]
  • Bagley SW [1]
  • Buckeridge C [1]
  • Corpina RA [1]
  • Craig T [1]
  • Curto JM [1]
  • Derksen DR [1]
  • Dias JM [1]
  • Edmonds DJ [1]
  • Fennell K [1]
  • Fortin JP [1]
  • Griffith DA [1]
  • Griffor MC [1]
  • Healy DR [1]
  • Huang Z [1]
  • Huynh KW [1]
  • Jackson VM [1]
  • Jove V [1]
  • Kalgutkar AS [1]
  • Kuzmiski JB [1]
  • Landis MS [1]
  • Lee CW [1]
  • Lettiere D [1]
  • Levine K [1]
  • Limberakis C [1]
  • Liu Y [1]
  • Mathiowetz AM [1]
  • Patel JC [1]
  • Piotrowski DW [1]
  • Plumb R [1]
  • Price DA [1]
  • Ralph EC [1]
  • Ruggeri RB [1]
  • Saxena AR [1]
  • Schenone M [1]
  • Tess DA [1]
  • Wang F [1]
  • Wes PD [1]
  • Wheeler H [1]
  • Wu H [1]
  • Yamaguchi M [1]

Author by ORCID

  • Yue WW [4]
  • Han S [4]
  • Mccorvie TJ [4]
  • Froese DS [4]
  • Berg AP [4]
  • Kalgutkar AS [1]
  • Ruggeri RB [1]
  • Piotrowski DW [1]
  • Bagley SW [1]
  • Griffith DA [1]
  • Limberakis C [1]

Journal

  • NAT STRUCT MOL BIOL [4]
  • BIORXIV [1]
  • J MED CHEM [1]

Software

  • RELION [5]
  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [5]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 6K X 4K [4]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • AlphaFold DB [6]
  • Gene Ontology [6]
  • InterPro [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Complex Portal [4]
  • ChEBI [3]
  • DrugBank [3]
  • ChEMBL [2]