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author:"Fernandes JS"

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  • Tamhane T [1]
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  • Haldrup Bjornsson K [1]
  • Fernandes JS [1]
  • Jenkins TP [1]
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  • Risager Christensen C [1]
  • Morell O [1]
  • Lacunza I [1]
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EMD-49573
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Cryo-EM structure of a de-novo designed binder NY1-B04 in complex with HLA-A 02:01 and NY-ESO-1-derived peptide SLLMWITQC
Release date: July 23, 2025
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 9nnf
Q-score: 0.449

Johansen KH, Wolff DS, Scapolo B, Fernandez-Quintero ML, Risager Christensen C, Loeffler JR, Rivera-de-Torre E, Overath MD, Kjaergaard Munk K, Morell O, Viuff MC, Lacunza I, Damm Englund AT, Due M, Gharpure A, Forli S, Rodriguez Pardo C, Tamhane T, Qingjie Andersen E, Haldrup Bjornsson K, Fernandes JS, Voss LF, Thumtecho S, Ward AB, Ormhoj M, Reker Hadrup S, Jenkins TP

Science (2025) 389 pp. 380-385 [ DOI: doi:10.1126/science.adv0422 Pubmed: 40705893 ]

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Preview first 10
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Filter By

Current Database

  • EMDB [1]

Current status

  • REL [1]

Sample type

  • Complex [1]
  • Protein [1]

Organism

  • Bacillus subtilis [1]
  • Synthetic construct [1]
  • Escherichia coli [1]
  • Homo sapiens [1]

EM Method

  • Single-particle [1]

Resolution

  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 50-100 kDa [1]

Release Date

  • 2025 [1]

Author by name

  • Damm Englund At [1]
  • Due M [1]
  • Fernandes JS [1]
  • Fernandez-quintero ML [1]
  • Forli S [1]
  • Gharpure A [1]
  • Haldrup Bjornsson K [1]
  • Jenkins TP [1]
  • Johansen KH [1]
  • Kjaergaard Munk K [1]
  • Lacunza I [1]
  • Loeffler JR [1]
  • Morell O [1]
  • Ormhoj M [1]
  • Overath MD [1]
  • Qingjie Andersen E [1]
  • Reker Hadrup S [1]
  • Risager Christensen C [1]
  • Rivera-de-torre E [1]
  • Rodriguez Pardo C [1]
  • Scapolo B [1]
  • Tamhane T [1]
  • Thumtecho S [1]
  • Viuff MC [1]
  • Voss LF [1]
  • Ward AB [1]
  • Wolff DS [1]

Author by ORCID

  • Tamhane T [1]
  • Ward AB [1]
  • Kjaergaard Munk K [1]
  • Rivera-de-torre E [1]
  • Ormhoj M [1]
  • Gharpure A [1]
  • Loeffler JR [1]
  • Reker Hadrup S [1]
  • Forli S [1]
  • Fernandez-quintero ML [1]
  • Johansen KH [1]
  • Thumtecho S [1]
  • Wolff DS [1]
  • Voss LF [1]
  • Haldrup Bjornsson K [1]
  • Fernandes JS [1]
  • Jenkins TP [1]
  • Viuff MC [1]
  • Risager Christensen C [1]
  • Morell O [1]
  • Lacunza I [1]
  • Rodriguez Pardo C [1]
  • Damm Englund At [1]
  • Due M [1]
  • Scapolo B [1]
  • Overath MD [1]

Journal

  • SCIENCE [1]

Microscope

  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [1]

Film or detector model

  • FEI FALCON IV 4K X 4K [1]

External links

  • AlphaFold DB [1]
  • Gene Ontology [1]
  • PDB [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]