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EMD-7868
Mu Opioid Receptor-Gi Protein Complex
EMD-7868
Single-particle3.5 Å
Deposition: 10/05/2018Map released: 13/06/2018
Last modified: 30/10/2024
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Ternary complex of DAMGO-activated Mu-type opioid receptor with heterotrimeric Gi, further stabilized by addition of Scfv-16
Fitted models: 6dde
Deposition Authors: Koehl A, Hu H
Sample: Ternary complex of DAMGO-activated Mu-type opioid receptor with heterotrimeric Gi, further stabilized by addition of Scfv-16
Fitted models: 6dde
Deposition Authors: Koehl A, Hu H
Structure of the mu-opioid receptor-Giprotein complex.
Koehl A,
Hu H,
Maeda S
,
Zhang Y
,
Qu Q,
Paggi JM,
Latorraca NR
,
Hilger D
,
Dawson R,
Matile H,
Schertler GFX
,
Granier S,
Weis WI
,
Dror RO,
Manglik A,
Skiniotis G
,
Kobilka BK
(2018) Nature , 558 , 547 - 552
,
Zhang Y
,
Qu Q,
Paggi JM,
Latorraca NR
,
Hilger D
,
Dawson R,
Matile H,
Schertler GFX
,
Granier S,
Weis WI
,
Dror RO,
Manglik A,
Skiniotis G
,
Kobilka BK
(2018) Nature , 558 , 547 - 552
Grant Support:
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): R37DA036246 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM083118 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): T32GM007276 (United States)
- Swiss National Science Foundation: 310030_153145 (Switzerland)
- Swiss National Science Foundation: 310030B_17335 (Switzerland)
