EMD-64912
Cryo-EM structure of human Neurotensin Receptor 1 (hNTSR1)-Gi1 complex in nucleotide-free NC state 3
EMD-64912
Single-particle3.31 Å
Deposition: 04/06/2025Map released: 03/06/2026
Last modified: 03/06/2026
Sample Organism:
Homo sapiens,
Mus musculus,
synthetic construct
Sample: JMV449-bound human Neurotensin Receptor 1 (hNTSR1)-Gi1 complex in nucleotide-free NC state 3 with scFv16
Fitted models: 9vb1
Deposition Authors: Kobayashi K
,
Matsui TE,
Fukuda M ,
Kawakami K ,
Yamashita K ,
Kato HE ,
Kato HE
Sample: JMV449-bound human Neurotensin Receptor 1 (hNTSR1)-Gi1 complex in nucleotide-free NC state 3 with scFv16
Fitted models: 9vb1
Deposition Authors: Kobayashi K
,
Matsui TE,
Fukuda M ,
Kawakami K ,
Yamashita K ,
Kato HE ,
Kato HE
The dynamic basis of G-protein recognition and activation by a GPCR.
Kobayashi K ,
Kawakami K ,
Matsui TE,
Yokoi S,
Fukuda M ,
Narita TJ,
Arai H,
Tambo M,
Sumikama T ,
Tatsumi M,
Yamashita K ,
Koyanagi J,
Kugawa M,
Ikeda H,
Sumino A,
Mitsutake A ,
Kobilka BK ,
Inoue A ,
Kato HE
(2026) Nature , 652 , 812 - 821
,
Kawakami K ,
Matsui TE,
Yokoi S,
Fukuda M ,
Narita TJ,
Arai H,
Tambo M,
Sumikama T ,
Tatsumi M,
Yamashita K ,
Koyanagi J,
Kugawa M,
Ikeda H,
Sumino A,
Mitsutake A ,
Kobilka BK ,
Inoue A ,
Kato HE
(2026) Nature , 652 , 812 - 821
Grant Support:
- Japan Society for the Promotion of Science (JSPS): 25K09525 (Japan)
- Japan Society for the Promotion of Science (JSPS): 24H02262 (Japan)
- Japan Society for the Promotion of Science (JSPS): 25H01338 (Japan)
- Japan Society for the Promotion of Science (JSPS): 24KJ0981 (Japan)
- Japan Society for the Promotion of Science (JSPS): 25H02243 (Japan)
- Japan Society for the Promotion of Science (JSPS): 24K18060 (Japan)
- Japan Society for the Promotion of Science (JSPS): 23KJ0363 (Japan)