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EMD-4983

Single-particle
3.5 Å
EMD-4983
3D View Gallery
Deposition: 15/05/2019
Map released: 08/01/2020
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-4983
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6rqj summary report (pdf.gz) Map and 6rqj FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1

EMD-4983

Single-particle
3.5 Å
EMD-4983
3D View Gallery
Deposition: 15/05/2019
Map released: 08/01/2020
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rhipicephalus pulchellus, Homo sapiens, Ornithodoros moubata, Rhipicephalus appendiculatus
Sample: Quaternary complex of human complement C5 with tick inhibitors OmCI, RaCI and CirpT1
Fitted models: 6rqj

Deposition Authors: Reichhardt MP , Johnson S
An inhibitor of complement C5 provides structural insights into activation.
Reichhardt MP , Johnson S , Tang T , Morgan T, Tebeka N , Popitsch N , Deme JC, Jore MM, Lea SM
(2020) PNAS , 117 , 362 - 370
PUBMED: 31871188
DOI: doi:10.1073/pnas.1909973116
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: