Protein Data Bank in Europe

Chain: A
Length: 999 amino acids
Theoretical weight: 112.64 KDa
Source organism: Homo sapiens
UniProt:

• Canonical: P01031 (Residues: 678-1676; Coverage: 60%)

Gene names: C5, CPAMD4
Sequence domains:

• Anaphylotoxin-like domain
• Alpha-2-macroglobulin family
• A-macroglobulin TED domain
• Complement component 5, CUB domain
• A-macroglobulin receptor binding domain
• UNC-6/NTR/C345C module

Chain: C
Length: 165 amino acids
Theoretical weight: 18.65 KDa
Source organism: Rhipicephalus pulchellus
Expression system: Kluyveromyces lactis
UniProt:

• Canonical: Q5YD59 (Residues: 1-1, 19-168; Coverage: 89%)

Chain: D
Length: 81 amino acids
Theoretical weight: 8.58 KDa
Source organism: Rhipicephalus pulchellus
Expression system: Escherichia coli
UniProt:

• Canonical: A0A141SFN4 (Residues: 21-98; Coverage: 100%)

Chain: B
Length: 655 amino acids
Theoretical weight: 73.36 KDa
Source organism: Homo sapiens
UniProt:

• Canonical: P01031 (Residues: 19-673; Coverage: 40%)

Gene names: C5, CPAMD4
Sequence domains:

• Macroglobulin domain MG1
• MG2 domain
• Macroglobulin domain MG3
• Macroglobulin domain MG4
• Alpha-2-macroglobulin bait region domain

Chain: E
Length: 112 amino acids
Theoretical weight: 12.15 KDa
Source organism: Rhipicephalus pulchellus
Expression system: Escherichia coli
UniProt:

• Canonical: L7MB58 (Residues: 24-111; Coverage: 96%)

Sequence domains: Single domain von Willebrand factor type C