EMD-22514

Single-particle
3.2 Å
EMD-22514
3D View Gallery
Deposition: 25/08/2020
Map released: 07/10/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22514

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7jwb summary report (pdf.gz) Map-7jwb FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

SARS CoV2 Spike ectodomain with engineered trimerized VH binder

EMD-22514

Single-particle
3.2 Å
EMD-22514
3D View Gallery
Deposition: 25/08/2020
Map released: 07/10/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Sample: Complex of SARS CoV2 Spike ectodomain with engineered trimerized VH domain
Fitted models: 7jwb

Deposition Authors: QCRG Structural Biology Consortium
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
Bracken CJ , Lim SA , Solomon P, Rettko NJ , Nguyen DP, Zha BS, Schaefer K, Byrnes JR , Zhou J, Lui I , Liu J, Pance K, Zhou XX, Leung KK , Wells JA
(2021) Nat Chem Biol , 17 , 113 - 121
PUBMED: 33082574
DOI: doi:10.1038/s41589-020-00679-1
ISSN: 1552-4469