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EMD-22514

Single-particle
3.2 Å
EMD-22514
3D View Gallery
Deposition: 25/08/2020
Map released: 07/10/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22514
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7jwb summary report (pdf.gz) Map and 7jwb FULL report (pdf.gz)
EMICSS annotations (xml)

SARS CoV2 Spike ectodomain with engineered trimerized VH binder

EMD-22514

Single-particle
3.2 Å
EMD-22514
3D View Gallery
Deposition: 25/08/2020
Map released: 07/10/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Sample: Complex of SARS CoV2 Spike ectodomain with engineered trimerized VH domain
Fitted models: 7jwb

Deposition Authors: QCRG Structural Biology Consortium
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
Bracken CJ , Lim SA , Solomon P, Rettko NJ , Nguyen DP, Zha BS, Schaefer K, Byrnes JR , Zhou J, Lui I , Liu J, Pance K, Zhou XX, Leung KK , Wells JA
(2021) Nat Chem Biol , 17 , 113 - 121
PUBMED: 33082574
DOI: doi:10.1038/s41589-020-00679-1
ISSN: 1552-4469