Electron Microscopy
6Å resolution

SARS CoV2 Spike ectodomain with engineered trimerized VH binder


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-210183 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
autonomous human heavy chain variable domain Chain: D
Molecule details ›
Chain: D
Length: 421 amino acids
Theoretical weight: 44.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1208 amino acids
Theoretical weight: 133.75 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Cricetulus griseus
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Relevant EMDB volumes: EMD-22514
Expression systems:
  • Escherichia coli K-12
  • Cricetulus griseus