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CHEBI:15940 - nicotinic acid
| Formula | C6H5NO2 |
| Net Charge | 0 |
| Average Mass | 123.111 |
| Monoisotopic Mass | 123.03203 |
| SMILES | O=C(O)c1cccnc1 |
| InChI | InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9) |
| InChIKey | PVNIIMVLHYAWGP-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. anti-obesity agent Any substance which is used to reduce or control weight. mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. EC 3.5.1.19 (nicotinamidase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19). human urinary metabolite Any metabolite (endogenous or exogenous) found in human urine samples. Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| Applications: | cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. hypoglycemic agent A drug which lowers the blood glucose level. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. renoprotective agent Any compound that is able to prevent damage to the kidneys. antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. antidote Any protective agent counteracting or neutralizing the action of poisons. anticholesteremic drug A substance used to lower plasma cholesterol levels. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). vasodilator agent A drug used to cause dilation of the blood vessels. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| nicotinic acid (CHEBI:15940) has role Escherichia coli metabolite (CHEBI:76971) |
| nicotinic acid (CHEBI:15940) has role analgesic (CHEBI:35480) |
| nicotinic acid (CHEBI:15940) has role anti-anaemic agent (CHEBI:75835) |
| nicotinic acid (CHEBI:15940) has role anti-HIV agent (CHEBI:64946) |
| nicotinic acid (CHEBI:15940) has role anti-obesity agent (CHEBI:74518) |
| nicotinic acid (CHEBI:15940) has role antiatherosclerotic agent (CHEBI:145947) |
| nicotinic acid (CHEBI:15940) has role anticholesteremic drug (CHEBI:35821) |
| nicotinic acid (CHEBI:15940) has role antidepressant (CHEBI:35469) |
| nicotinic acid (CHEBI:15940) has role antidote (CHEBI:50247) |
| nicotinic acid (CHEBI:15940) has role antilipemic drug (CHEBI:35679) |
| nicotinic acid (CHEBI:15940) has role antineoplastic agent (CHEBI:35610) |
| nicotinic acid (CHEBI:15940) has role antipsychotic agent (CHEBI:35476) |
| nicotinic acid (CHEBI:15940) has role antitubercular agent (CHEBI:33231) |
| nicotinic acid (CHEBI:15940) has role anxiolytic drug (CHEBI:35474) |
| nicotinic acid (CHEBI:15940) has role cardiovascular drug (CHEBI:35554) |
| nicotinic acid (CHEBI:15940) has role EC 3.5.1.19 (nicotinamidase) inhibitor (CHEBI:84264) |
| nicotinic acid (CHEBI:15940) has role human urinary metabolite (CHEBI:84087) |
| nicotinic acid (CHEBI:15940) has role hypoglycemic agent (CHEBI:35526) |
| nicotinic acid (CHEBI:15940) has role metabolite (CHEBI:25212) |
| nicotinic acid (CHEBI:15940) has role mouse metabolite (CHEBI:75771) |
| nicotinic acid (CHEBI:15940) has role plant metabolite (CHEBI:76924) |
| nicotinic acid (CHEBI:15940) has role renoprotective agent (CHEBI:231911) |
| nicotinic acid (CHEBI:15940) has role vasodilator agent (CHEBI:35620) |
| nicotinic acid (CHEBI:15940) is a pyridine alkaloid (CHEBI:26416) |
| nicotinic acid (CHEBI:15940) is a pyridinemonocarboxylic acid (CHEBI:26420) |
| nicotinic acid (CHEBI:15940) is a vitamin B3 (CHEBI:176839) |
| nicotinic acid (CHEBI:15940) is conjugate acid of nicotinate (CHEBI:32544) |
| Incoming Relation(s) |
| Euphorbia diterpenoid 2 (CHEBI:65884) has functional parent nicotinic acid (CHEBI:15940) |
| N-methylnicotinic acid (CHEBI:50521) has functional parent nicotinic acid (CHEBI:15940) |
| myo-inositol hexanicotinate (CHEBI:31699) has functional parent nicotinic acid (CHEBI:15940) |
| D-ribosylnicotinic acid (CHEBI:27748) has functional parent nicotinic acid (CHEBI:15940) |
| 1,4,5,6-tetrahydro-6-oxonicotinic acid (CHEBI:16453) has functional parent nicotinic acid (CHEBI:15940) |
| 2-aminonicotinic acid (CHEBI:68572) has functional parent nicotinic acid (CHEBI:15940) |
| 2,6-dihydroxynicotinic acid (CHEBI:49087) has functional parent nicotinic acid (CHEBI:15940) |
| 4-aminonicotinic acid (CHEBI:68577) has functional parent nicotinic acid (CHEBI:15940) |
| 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CHEBI:17693) has functional parent nicotinic acid (CHEBI:15940) |
| 5-aminonicotinic acid (CHEBI:68578) has functional parent nicotinic acid (CHEBI:15940) |
| 5-hydroxy-6-methylpyridine-3-carboxylic acid (CHEBI:15821) has functional parent nicotinic acid (CHEBI:15940) |
| 5-pyridoxic acid (CHEBI:16409) has functional parent nicotinic acid (CHEBI:15940) |
| 6-aminonicotinic acid (CHEBI:68583) has functional parent nicotinic acid (CHEBI:15940) |
| 6-hydroxynicotinic acid (CHEBI:16168) has functional parent nicotinic acid (CHEBI:15940) |
| benzyl nicotinate (CHEBI:31268) has functional parent nicotinic acid (CHEBI:15940) |
| boscalid (CHEBI:81822) has functional parent nicotinic acid (CHEBI:15940) |
| clonixin (CHEBI:76200) has functional parent nicotinic acid (CHEBI:15940) |
| cyclitol nicotinate (CHEBI:50135) has functional parent nicotinic acid (CHEBI:15940) |
| flunixin (CHEBI:76138) has functional parent nicotinic acid (CHEBI:15940) |
| hyponine D (CHEBI:132388) has functional parent nicotinic acid (CHEBI:15940) |
| hyponine E (CHEBI:132389) has functional parent nicotinic acid (CHEBI:15940) |
| inositol hexanicotinate (CHEBI:33064) has functional parent nicotinic acid (CHEBI:15940) |
| nicotinamide (CHEBI:17154) has functional parent nicotinic acid (CHEBI:15940) |
| regelidine (CHEBI:132396) has functional parent nicotinic acid (CHEBI:15940) |
| vitamin B complex (CHEBI:75782) has part nicotinic acid (CHEBI:15940) |
| nicotinic-d4 acid (CHEBI:145116) is a nicotinic acid (CHEBI:15940) |
| nicotinate (CHEBI:32544) is conjugate base of nicotinic acid (CHEBI:15940) |
| IUPAC Names |
|---|
| nicotinic acid |
| pyridine-3-carboxylic acid |
| INNs | Source |
|---|---|
| acide nicotinique | WHO MedNet |
| ácido nicotínico | WHO MedNet |
| acidum nicotinicum | WHO MedNet |
| nicotinic acid | WHO MedNet |
| Synonyms | Source |
|---|---|
| 3-carboxylpyridine | ChemIDplus |
| 3-carboxypyridine | NIST Chemistry WebBook |
| 3-pyridinecarboxylic acid | KEGG COMPOUND |
| 3-Pyridylcarboxylic acid | HMDB |
| anti-pellagra vitamin | NIST Chemistry WebBook |
| m-pyridinecarboxylic acid | NIST Chemistry WebBook |
| Brand Names | Source |
|---|---|
| Niacin component of advicor | ChEMBL |
| Niacin component of simcor | ChEMBL |
| Niacin td | ChEMBL |
| Niacor | KEGG DRUG |
| Niaspan | KEGG DRUG |
| Niaspan er | ChEMBL |
| Citations |
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