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CHEBI:142118 - imidazobenzodiazepine
| ChEBI ID | CHEBI:142118 |
| ChEBI Name | imidazobenzodiazepine |
| Stars | |
| Definition | Any organic heterotricyclic compound that is any benzodiazepine which is ortho-fused with a imidazole. |
| Last Modified | 11 November 2019 |
| Submitter | Adnan |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| imidazobenzodiazepine (CHEBI:142118) is a benzodiazepine (CHEBI:22720) |
| imidazobenzodiazepine (CHEBI:142118) is a organic heterotricyclic compound (CHEBI:26979) |
| Incoming Relation(s) |
| 1-hydroxymidazolam (CHEBI:145330) is a imidazobenzodiazepine (CHEBI:142118) |
| 1-hydroxymidazolam β-D-glucuronide (CHEBI:145334) is a imidazobenzodiazepine (CHEBI:142118) |
| 1',4-dihydroxymidazolam (CHEBI:145332) is a imidazobenzodiazepine (CHEBI:142118) |
| 4-hydroxymidazolam (CHEBI:145331) is a imidazobenzodiazepine (CHEBI:142118) |
| 4-hydroxymidazolam β-D-glucuronide (CHEBI:145335) is a imidazobenzodiazepine (CHEBI:142118) |
| flumazenil (CHEBI:5103) is a imidazobenzodiazepine (CHEBI:142118) |
| iomazenil (123I) (CHEBI:135665) is a imidazobenzodiazepine (CHEBI:142118) |
| loprazolam (CHEBI:135754) is a imidazobenzodiazepine (CHEBI:142118) |
| midazolam (CHEBI:6931) is a imidazobenzodiazepine (CHEBI:142118) |
| midazolam hydrochloride (CHEBI:6932) is a imidazobenzodiazepine (CHEBI:142118) |
| Synonym | Source |
|---|---|
| imidazobenzodiazepines | ChEBI |