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CHEBI:135665 - iomazenil (123I)

ChEBI IDCHEBI:135665
ChEBI Nameiomazenil (123I)
Stars
ASCII Nameiomazenil ((123)I)
Last Modified6 September 2018
DownloadsMolfile
FormulaC15H14N3O3
Net Charge0
Average Mass407.201
Monoisotopic Mass407.00911
SMILESCCOC(=O)c1ncn2c1CN(C)C(=O)c1c([123I])cccc1-2
InChIInChI=1S/C15H14IN3O3/c1-3-22-15(21)13-11-7-18(2)14(20)12-9(16)5-4-6-10(12)19(11)8-17-13/h4-6,8H,3,7H2,1-2H3/i16-4
InChIKeyFRIZVHMAECRUBR-KIWWSDKQSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
iomazenil (123I) (CHEBI:135665) is a imidazobenzodiazepine (CHEBI:142118)
Synonym  Source
iomazenilDrugCentral
Manual XrefsDatabases
1462DrugCentral
Registry NumbersSources
CAS:127396-36-5DrugCentral