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CHEBI:135754 - loprazolam

ChEBI IDCHEBI:135754
ChEBI Nameloprazolam
Stars
Last Modified5 September 2018
DownloadsMolfile
FormulaC23H21ClN6O3
Net Charge0
Average Mass464.913
Monoisotopic Mass464.13637
SMILESCN1CCN(/C=C2\N=C3CN=C(c4ccccc4Cl)c4cc([N+](=O)[O-])ccc4N3C2=O)CC1
InChIInChI=1S/C23H21ClN6O3/c1-27-8-10-28(11-9-27)14-19-23(31)29-20-7-6-15(30(32)33)12-17(20)22(25-13-21(29)26-19)16-4-2-3-5-18(16)24/h2-7,12,14H,8-11,13H2,1H3/b19-14-
InChIKeyUTEFBSAVJNEPTR-RGEXLXHISA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
loprazolam (CHEBI:135754) is a imidazobenzodiazepine (CHEBI:142118)
Synonyms  Source
loprazolam mesilateDrugCentral
loprazolam mesylateDrugCentral
Manual XrefsDatabases
1602DrugCentral
Registry NumbersSources
CAS:61197-73-7DrugCentral