Chiorino2002 - G1/S transition model

Model Identifier
MODEL2003180003
Short description
mathematical approach to model the protein interactions regulating the transition from the G1 phase to the phase of DNA synthesis. Model is encoded by matthieu Maire and submitted to BioModels by krishna kumar tiwari.
Format
SBML
(L2V4)
Related Publication
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Variability in the timing of G(1)/S transition.
- Chiorino G, Lupi M
- Mathematical biosciences , 1/ 2002 , Volume 177-178 , pages: 85-101 , PubMed ID: 11965250
- Biomathematics Unit, Laboratory of Cancer Pharmacogenomics, Edo Tempia Foundation-SENDO, via Malta 3, 13900 Biella, Italy. giochiorino@hotmail.com
- Cell cycle duration and phase transition times are not fixed, even within homogeneous cell populations growing under optimal environmental conditions. We investigate G(1) phase variability from the molecular point of view and propose a mathematical approach to model the protein interactions regulating the transition from the G(1) phase to the phase of DNA synthesis. The mathematical model has some connections with flow cytometry experimental data.
Contributors
Submitter of the first revision: Krishna Kumar Tiwari
Submitter of this revision: Krishna Kumar Tiwari
Modellers: Krishna Kumar Tiwari
Submitter of this revision: Krishna Kumar Tiwari
Modellers: Krishna Kumar Tiwari
Metadata information
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Curation status
Non-curated
Modelling approach(es)
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