March, 2021
Ito2019 - Gefitinib resistance of lung adenocarcinoma caused by MET amplification
Model(s) associated with this Model of the Month: BIOMD0000000827
Last updated by: Krishna Kumar Tiwari
BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats. Our mission is to provide the systems modelling community with reproducible, high-quality, freely-accessible models published in the scientific literature. More information about using BioModels such as model submission, update, publication can be found in the FAQ.
Highlight Features
1,004 models
1,267 models
833 models
1,132 classes
228,842 records
Recently published
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Dudziuk2019 - Biologically sound formal model of Hsp70 heat induction
Submitter: Krishna Kumar Tiwari | Published date: 2021-04-22Publication: Biologically sound formal model of Hsp70 heat induction., Journal of theoretical biology (2019) -
Scaramellini1997 - Two-receptor:One-transducer (2R1T) model for analysis of interactions between agonists
Submitter: Kausthubh Ramachandran | Published date: 2021-06-08Publication: Analysis of agonist-agonist interactions: the crucial influence of curve shape., Journal of pharmacological and toxicological methods (1997) -
Renz2020 - GEM of Human alveolar macrophage with SARS-CoV-2
Submitter: Rahuman Sheriff | Published date: 2021-04-30Publication: FBA reveals guanylate kinase as a potential target for antiviral therapies against SARS-CoV-2, Bioinformatics (2020) -
Zhang2007 - Mechanism of DNA damage response (Model1)
Submitter: Krishna Kumar Tiwari | Published date: 2021-05-26Publication: Exploring mechanisms of the DNA-damage response: p53 pulses and their possible relevance to apoptosis., Cell cycle (Georgetown, Tex.) (2007) -
DalviGarcia2021 - Dopaminergic and Serotonergic-Kynurenine model
Submitter: Krishna Kumar Tiwari | Published date: 2021-05-11Publication: A model of dopamine and serotonin-kynurenine metabolism in cortisolemia: Implications for depression, PLOS Computational Biology (2021) -
Mani-Tlusty2021 - generative development model
Submitter: Krishna Kumar Tiwari | Published date: 2021-05-24Publication: A comprehensive survey of developmental programs reveals a dearth of tree-like lineage graphs and ubiquitous regeneration, BMC Biology (2021) -
Corbat2021 - Apoptotic Reaction Model.models
Submitter: Agustin | Published date: 2021-05-26Publication: An Integrative Apoptotic Reaction Model for extrinsic and intrinsic stimuli, biorXiv (2021)
Recently accessed
- Izhikevich2004_SpikingNeurons_Class2Excitable
- Haffez2017 - RAR interaction with synthetic analogues
- Hettling2011_CreatineKinase
- Haberichter2007_cellcycle
- Novak1997 - Cell Cycle
- Talemi2014 - Arsenic toxicity and detoxification mechanisms in yeast
- Brännmark2013 - Insulin signalling in human adipocytes (normal condition)
- Stortelder1997 - Thrombin Generation Amidolytic Activity
- Legewie2006_apoptosis_WT
- Bungay2003_Thrombin_Generation
News
- 27/02/2021: Reproducibility in Systems Biology Modelling manuscript published
- 23/07/2020: Retirement party for the classic BioModels website
- 19/06/2020: New updates for Release 5.1.9
- 10/06/2020: New updates for Release 5.1.8
- 05/06/2020: BioModels Parameters Manuscript accepted
- 17/01/2020: Planned maintenance
- 12/06/2018: Planned upgrades to BioModels
- 21/08/2017: Patient-derived genome-scale metabolic models
- 26/06/2017: 31st release of BioModels
- 16/01/2017: Metabolic networks and logical models have been published
How to cite BioModels
- Rahuman S Malik-Sheriff, Mihai Glont, Tung V N Nguyen, Krishna Tiwari, Matthew G Roberts, Ashley Xavier, Manh T Vu, Jinghao Men, Matthieu Maire, Sarubini Kananathan, Emma L Fairbanks, Johannes P Meyer, Chinmay Arankalle, Thawfeek M Varusai, Vincent Knight-Schrijver, Lu Li, Corina Dueñas-Roca, Gaurhari Dass, Sarah M Keating, Young M Park, Nicola Buso, Nicolas Rodriguez, Michael Hucka, and Henning Hermjakob
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Nucl. Acids Res. 2020
- Mihai Glont, Tung V N Nguyen, Martin Graesslin, Robert Hälke, Raza Ali, Jochen Schramm, Sarala M Wimalaratne, Varun B Kothamachu, Nicolas Rodriguez, Maciej J Swat, Jurgen Eils, Roland Eils, Camille Laibe, Rahuman S Malik-Sheriff, Vijayalakshmi Chelliah, Nicolas Le Novère, and Henning Hermjakob
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Nucl. Acids Res. 2018
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BioModels provides online courses, please consult more information.
Acknowledgements
- BioModels is supported by the European Molecular Biology Laboratory, the Biotechnology and Biological Sciences Research Council (Multimod, BB/N019482/1) and the Innovative Medicines Initiative (TransQST, 116030).
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