Application closed for "Model of the year" Competition 2024. Evaluation under progress!

BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats. Our mission is to provide the systems modelling community with reproducible, high-quality, freely-accessible models published in the scientific literature. More information about using BioModels such as model submission, update, publication, or reviewers access can be found in the FAQ.

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1,132 classes
1,073 models
1,598 models
833 models
1,132 classes

Model of The Month

August, 2024

Protein synthesis and post-translational modification

Pulsed stable isotope labelling of amino acids in cell culture (pSILAC) is used to analyze protein turnover and post-translational modifications (PTMs). This model demonstrated that for proteins with multiple interconvertible forms, such data can only reveal the sequence of modifications rather than direct differences in stability.

Model(s) associated with this Model of the Month: BIOMD0000001078.

Last updated by: Eva-Maria Geissen


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Rahuman S Malik-Sheriff, Mihai Glont, Tung V N Nguyen, Krishna Tiwari, Matthew G Roberts, Ashley Xavier, Manh T Vu, Jinghao Men, Matthieu Maire, Sarubini Kananathan, Emma L Fairbanks, Johannes P Meyer, Chinmay Arankalle, Thawfeek M Varusai, Vincent Knight-Schrijver, Lu Li, Corina Dueñas-Roca, Gaurhari Dass, Sarah M Keating, Young M Park, Nicola Buso, Nicolas Rodriguez, Michael Hucka, and Henning Hermjakob
Nucl. Acids Res. 2020
Mihai Glont, Tung V N Nguyen, Martin Graesslin, Robert Hälke, Raza Ali, Jochen Schramm, Sarala M Wimalaratne, Varun B Kothamachu, Nicolas Rodriguez, Maciej J Swat, Jurgen Eils, Roland Eils, Camille Laibe, Rahuman S Malik-Sheriff, Vijayalakshmi Chelliah, Nicolas Le Novère, and Henning Hermjakob
Nucl. Acids Res. 2018
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