Khanin1998 - Mathematical Model of Blood Coagulation Prothrombin Time Test
Model Identifier
MODEL1806120001
Short description
Blood coagulation model for prothrombin time test.
Format
SBML
(L2V4)
Related Publication
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Mathematical model for the blood coagulation prothrombin time test.
- Khanin MA, Rakov DV, Kogan AE
- Thrombosis research , 3/ 1998 , Volume 89 , Issue 5 , pages: 227-232 , PubMed ID: 9645916
- Laboratory of Theoretical Biology, Russian State University of Technology, Moscow. khanin@landau.ac.ru
- A mathematical model for the prothrombin time test is proposed. The time course of clotting factor activation during coagulation was calculated, and the sensitivity of the test to a decrease in the concentrations of coagulation proteins or their activities was studied. The model predicts that only severe coagulation disorders connected with a more than five-fold decrease in the concentrations or activities of the blood coagulation factors can be revealed by the test.
Contributors
Submitter of the first revision: Matthew Roberts
Submitter of this revision: Matthew Roberts
Modellers: Matthew Roberts
Submitter of this revision: Matthew Roberts
Modellers: Matthew Roberts
Metadata information
isDescribedBy (1 statement)
hasTaxon (1 statement)
isVersionOf (1 statement)
isPropertyOf (1 statement)
hasTaxon (1 statement)
isVersionOf (1 statement)
isPropertyOf (1 statement)
Curation status
Non-curated
Tags
Connected external resources
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| Name | Description | Size | Actions |
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Model files |
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| Khanin1998.xml | SBML L2V4 representation of Khanin1998 - Mathematical Model of Blood Coagulation Prothrombin Time Test | 44.13 KB | Preview | Download |
Additional files |
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| Khanin1998.cps | Noncurated model COPASI file. Model encoded using reactions in table 1. There appears to be discrepancies between the reactions listed in table 1, the pathway scheme and the example ODE. | 122.65 KB | Preview | Download |
- Model originally submitted by : Matthew Roberts
- Submitted: Jun 12, 2018 11:53:39 AM
- Last Modified: Jun 12, 2018 11:53:39 AM
Revisions
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Version: 2
- Submitted on: Jun 12, 2018 11:53:39 AM
- Submitted by: Matthew Roberts
- With comment: Edited model metadata online.