Model Identifier
MODEL1707110689
Short description

This is a whole genome metabolism model of a male patient diagnosed at the age of NaN years with Stomach Adenocarcinoma affecting the patient's stomach.

This model was automatically generated by tINIT (Agren, R., et al. (2014). Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling. Mol Syst Biol; 10(3), 721.) using information coming from the sample TCGA-3M-AB46-01A from GDC Portal (Initial release 1.0, accessed via GDC API) and, where relevant, augmented with metabolic pathway information extracted from Human Metabolic Atlas.

This model has been produced by Human Pathology Atlas project ( Uhlen, M., et al.; A pathology atlas of the human cancer transcriptome. Science.) and is currently hosted on BioModels Database and identified by MODEL1707110689.

Other models with the same disease include MODEL1707112576 MODEL1707112577 MODEL1707112578 MODEL1707112579 MODEL1707112580 MODEL1707113083 MODEL1707113084 MODEL1707113085 MODEL1707113086 MODEL1707113087 MODEL1707113088 MODEL1707113089 MODEL1707113090 MODEL1707113091 MODEL1707113092 MODEL1707113093 MODEL1707113094 MODEL1707113095 MODEL1707113096 MODEL1707113097 MODEL1707113098 MODEL1707113099 MODEL1707113100 MODEL1707113101 MODEL1707113102 MODEL1707113103 MODEL1707113104 MODEL1707113105 MODEL1707113106 MODEL1707113107 MODEL1707113108 MODEL1707113109 MODEL1707113110 MODEL1707113111 MODEL1707113112 MODEL1707113113 MODEL1707113114 MODEL1707113115 MODEL1707113116 MODEL1707113117 MODEL1707113118 MODEL1707113119 MODEL1707113120 MODEL1707113121 MODEL1707113122 MODEL1707113123 MODEL1707113124 MODEL1707113125 MODEL1707113126 MODEL1707113127 MODEL1707113128 MODEL1707113129 MODEL1707113130 MODEL1707113131 MODEL1707113132 MODEL1707113133 MODEL1707113134 MODEL1707113135 MODEL1707113136 MODEL1707113137 MODEL1707113138 MODEL1707113139 MODEL1707113140 MODEL1707113141 MODEL1707113142 MODEL1707113143 MODEL1707113144 MODEL1707113145 MODEL1707113146 MODEL1707113147 MODEL1707113148 MODEL1707113149 MODEL1707113150 MODEL1707113151 MODEL1707113152 MODEL1707113153 MODEL1707113154 MODEL1707113155 MODEL1707113156 MODEL1707113157 MODEL1707113158 MODEL1707113159 MODEL1707113160 MODEL1707113161 MODEL1707113162 MODEL1707113163 MODEL1707113164 MODEL1707113165 MODEL1707113166 MODEL1707113167 MODEL1707113168 MODEL1707113169 MODEL1707113170 MODEL1707113171 MODEL1707113172 MODEL1707113173 MODEL1707113174 MODEL1707113352 MODEL1707113353 MODEL1707113354 MODEL1707113355 MODEL1707113356 MODEL1707113357 MODEL1707113358 MODEL1707113359 MODEL1707113360 MODEL1707113361 MODEL1707113362 MODEL1707113363 MODEL1707113364 MODEL1707113365 MODEL1707113366 MODEL1707113367 MODEL1707113368 MODEL1707113369 MODEL1707113370 MODEL1707113371 MODEL1707113372 MODEL1707113373 MODEL1707113374 MODEL1707113400 MODEL1707113401 MODEL1707113402 MODEL1707113403 MODEL1707113404 MODEL1707113405 MODEL1707113406 MODEL1707113407 MODEL1707113408 MODEL1707113409 MODEL1707113410 MODEL1707113411 MODEL1707113412 MODEL1707113413 MODEL1707113414 MODEL1707113415 MODEL1707113416 MODEL1707113417 MODEL1707113418 MODEL1707113419 MODEL1707113420 MODEL1707113421 MODEL1707113422 MODEL1707113423 MODEL1707113424 MODEL1707113425 MODEL1707113927 MODEL1707113928 MODEL1707113929 MODEL1707113930 MODEL1707113931 MODEL1707113932 MODEL1707113933 MODEL1707113934 MODEL1707113935 MODEL1707113936 MODEL1707113937 MODEL1707113938 MODEL1707113939 MODEL1707113940 MODEL1707113941 MODEL1707113942 MODEL1707113943 MODEL1707113944 MODEL1707113945 MODEL1707113946 MODEL1707113947 MODEL1707113948 MODEL1707113949 MODEL1707113950 MODEL1707113951 MODEL1707113952 MODEL1707113953 MODEL1707113954 MODEL1707113955 MODEL1707113956 MODEL1707113957 MODEL1707114938 MODEL1707115073 MODEL1707115074 MODEL1707115075 MODEL1707115208 MODEL1707115209 MODEL1707115210 MODEL1707115211 MODEL1707115212 MODEL1707115213 MODEL1707115214 MODEL1707115215 MODEL1707115216 MODEL1707115217 MODEL1707115554 MODEL1707115555 MODEL1707115556 MODEL1707115557 MODEL1707115577 MODEL1707115578 MODEL1707115579 MODEL1707115580 MODEL1707115581 MODEL1707115582 MODEL1707115583 MODEL1707115584 MODEL1707115585 MODEL1707115586 MODEL1707115587 MODEL1707115588 MODEL1707115589 MODEL1707115590 MODEL1707115591 MODEL1707115592 MODEL1707115593 MODEL1707115594 MODEL1707115595 MODEL1707115596 MODEL1707115597 MODEL1707115598 MODEL1707115599 MODEL1707115600 MODEL1707115601 MODEL1707115602 MODEL1707115686 MODEL1707115687 MODEL1707115688 MODEL1707115689 MODEL1707115690 MODEL1707115691 MODEL1707115692 MODEL1707115693 MODEL1707115694 MODEL1707115695 MODEL1707115696 MODEL1707115697 MODEL1707115698 MODEL1707115699 MODEL1707115700 MODEL1707115701 MODEL1707115796 MODEL1707115797 MODEL1707115798 MODEL1707115799 MODEL1707116045 MODEL1707116046 MODEL1707116047 MODEL1707116048 MODEL1707116198 MODEL1707116199 MODEL1707116200 MODEL1707116201 MODEL1707116202 MODEL1707116203 MODEL1707116214 MODEL1707116215 MODEL1707116216 MODEL1707116217 MODEL1707116218 MODEL1707116219 MODEL1707116220 MODEL1707116221 MODEL1707116222 MODEL1707116223 MODEL1707116224 MODEL1707116225 MODEL1707116226 MODEL1707116227 MODEL1707116262 MODEL1707116263 MODEL1707116412 MODEL1707116413 MODEL1707116414 MODEL1707116415 MODEL1707116416 MODEL1707116417 MODEL1707116418 MODEL1707116419 MODEL1707116420 MODEL1707116421 MODEL1707116422 MODEL1707116423 MODEL1707116424 MODEL1707116425 MODEL1707116426 MODEL1707116427 MODEL1707116428 MODEL1707116429 MODEL1707116430 MODEL1707116431 MODEL1707116432 MODEL1707116433 MODEL1707116434 MODEL1707116435 MODEL1707116436 MODEL1707116437 MODEL1707116438 MODEL1707116439 MODEL1707116440 MODEL1707116441 MODEL1707116442 MODEL1707116443 MODEL1707116444 MODEL1707116445 MODEL1707116446 MODEL1707116447 MODEL1707116448 MODEL1707116449 MODEL1707116450 MODEL1707116451 MODEL1707116452 MODEL1707116453 MODEL1707116454 MODEL1707116455 MODEL1707116456 MODEL1707116457 MODEL1707116458 MODEL1707116459 MODEL1707116460 MODEL1707116679 MODEL1707116747 .

To cite BioModels, please use: V Chelliah et al; BioModels: ten-year anniversary. Nucleic Acids Res 2015; 43 (D1): D542-D548.

To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.
Format
SBML (L2V3)
Related Publication
  • A pathology atlas of the human cancer transcriptome. Click here to expand
  • Mathias Uhlen, Cheng Zhang, Sunjae Lee, Evelina Sjöstedt, Linn Fagerberg, Gholamreza Bidkhori, Rui Benfeitas, Muhammad Arif, Zhengtao Liu, Fredrik Edfors, Kemal Sanli, Kalle von Feilitzen, Per Oksvold, Emma Lundberg, Sophia Hober, Peter Nilsson, Johanna Mattsson, Jochen M Schwenk, Hans Brunnström, Bengt Glimelius, Tobias Sjöblom, Per-Henrik Edqvist, Dijana Djureinovic, Patrick Micke, Cecilia Lindskog, Adil Mardinoglu, Fredrik Ponten
  • Science (New York, N.Y.) , 8/ 2017 , Volume 357 , Issue 6352 , pages: eaan2507 , PubMed ID: 28818916
  • Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, Sweden. mathias.uhlen@scilifelab.se.
  • Cancer is one of the leading causes of death, and there is great interest in understanding the underlying molecular mechanisms involved in the pathogenesis and progression of individual tumors. We used systems-level approaches to analyze the genome-wide transcriptome of the protein-coding genes of 17 major cancer types with respect to clinical outcome. A general pattern emerged: Shorter patient survival was associated with up-regulation of genes involved in cell growth and with down-regulation of genes involved in cellular differentiation. Using genome-scale metabolic models, we show that cancer patients have widespread metabolic heterogeneity, highlighting the need for precise and personalized medicine for cancer treatment. All data are presented in an interactive open-access database (www.proteinatlas.org/pathology) to allow genome-wide exploration of the impact of individual proteins on clinical outcomes.
Contributors
Submitter of the first revision: Adil Mardinoglu
Submitter of this revision: Adil Mardinoglu
Curator: Adil Mardinoglu

Metadata information

is (1 statement)
BioModels Database MODEL1707110689

hasTaxon (1 statement)
Taxonomy Homo sapiens

hasProperty (3 statements)
Human Disease Ontology gastric adenocarcinoma
Mathematical Modelling Ontology Constraint-based model
PATO male

isDerivedFrom (2 statements)
BioModels Database MODEL1402200003
Genomic Data Commons Data Portal be6531b2-d1f3-44ab-9c02-1ceae51ef2bb

Curation status
Non-curated
Tags
Auto-Generated

Connected external resources