Turner2015-Human/Mosquito ELP Model

  public model
Model Identifier
BIOMD0000000922
Short description 
the growth of the mosquito population is directly related to the spread of malaria, the Four Stage Life Cycle is incorporated to model the effects of climate change and interspecies competition within the mosquito life cycle stages of Egg, Larvae, and Pupae.
Format
SBML (L2V4)
Related Publication
  • A comprehensive model of spread of malaria in humans and mosquitos
  • Amy Turner, Chanok Jung, Pan Tan, Srinivas Gotika, Vijay Mago
  • IEEE , 6/ 2015 , DOI: 10.1109/SECON.2015.7132968
  • Department of Computer Science, Troy University, AL - 36082, USA.
  • Mathematical models have the capability to incorporate statistical data so that infectious diseases can be studied in-depth. In this article, we use mathematical modeling to study malaria through a combination of the Susceptible, Exposed, Infectious and Recovered (SEIR) Model for humans; Susceptible, Exposed and Infectious (SEI) Model for mosquitos; and the Four Stage Life Cycle Model of the mosquito. Due to the fact that malaria is spread to humans through the bite of a female mosquito that has been infected by the plasmodium parasite, the impacts of mosquitos are also studied in this paper using the SEI Model. Finally, the growth of the mosquito population is directly related to the spread of malaria, the Four Stage Life Cycle is incorporated to model the effects of climate change and interspecies competition within the mosquito life cycle stages of Egg, Larvae, and Pupae. The combination of these models are used to show the growth and spread of malaria.
Contributors
Submitter of the first revision: Ahmad Zyoud
Submitter of this revision: Ahmad Zyoud
Modellers: Ahmad Zyoud

Metadata information

is (2 statements)
BioModels Database MODEL2003130001
BioModels Database BIOMD0000000922

hasProperty (5 statements)
Mathematical Modelling Ontology Ordinary differential equation model
NCIt Malaria
OMIT 0009103
NCIt Study Population
NCIt Disease Transmission

hasPart (1 statement)
Experimental Factor Ontology malaria

hasTaxon (1 statement)
isDescribedBy (1 statement)
Curation status
Curated
Modelling approach(es)
ordinary differential equation model
Tags

Connected external resources

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Name Description Size Actions

Model files
Turner2015_ELP.xml SBML L2V4 file Turner2015-Human/Mosquito ELP Model_Curated 26.44 KB Preview | Download

Additional files
Turner2015_ELP.cps COPASI version 4.27 (Build 217) Turner2015-Human/Mosquito ELP Model_Curated 53.79 KB Preview | Download
Turner2015_ELP.sedml sed-ml L1V2 Turner2015-Human/Mosquito ELP Model_Curated 1.01 KB Preview | Download

  • Model originally submitted by : Ahmad Zyoud
  • Submitted: Mar 13, 2020 5:08:35 PM
  • Last Modified: Mar 13, 2020 5:08:35 PM
Revisions
  • Version: 2 public model Download this version
    • Submitted on: Mar 13, 2020 5:08:35 PM
    • Submitted by: Ahmad Zyoud
    • With comment: Automatically added model identifier BIOMD0000000922
Legends
: Variable used inside SBML models


Species
Species Initial Concentration/Amount
Population of Larvae

MIRO 30000028 		5000.0 mmol
Population of Eggs

MIRO 30000049 		10000.0 mmol
Population of Pupae

MIRO 30000050 		3000.0 mmol
Reactions
Reactions Rate Parameters
=> Population_of_Larvae; Population_of_Eggs compartment*((Population_of_Eggs*Te-Population_of_Larvae*(Tl+Ml))-K0*Population_of_Larvae^2) Te = 0.361; Ml = 0.0501; K0 = 2.0E-4; Tl = 0.134
=> Population_of_Eggs compartment*(Ar*ep-Population_of_Eggs*(Te+Me)) Te = 0.361; ep = 30.0; Me = 0.05; Ar = 20.0
=> Population_of_Pupae; Population_of_Larvae compartment*(Population_of_Larvae*Tl-Population_of_Pupae*(Tp+Mp)) Tl = 0.134; Tp = 0.342; Mp = 0.0025
Curator's comment:
(added: 13 Mar 2020, 17:08:13, updated: 13 Mar 2020, 17:08:13)
The figure 5 represent the ELP model from the paper. the figure has been reproduced successfully without any modifications