EMDB EMD-9942

Single particle reconstruction
2.84Å resolution

Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1P state)

Map released:
Last modified:
Overview of EMD-9942
Source organism: Homo sapiens [9606]
Fitted atomic model: 6k7n
Primary publication:
Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Hiraizumi M, Yamashita K, Nishizawa T, Nureki O
Science 365 1149-1155 (2019)
PMID: 31416931

Function and Biology Details

Sample name: ATP8A1-CDC50a
Ligands: TETRAFLUOROALUMINATE ION, CHOLESTEROL HEMISUCCINATE, MAGNESIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: ATP8A1-CDC50a, Phospholipid-transporting ATPase, Cell cycle control protein 50A

Experimental Information Details

Resolution: 2.84Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: OTHER