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Single particle reconstruction
3.3Å resolution

Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class1)

Map released:
Last modified:
Overview of EMD-9931
Source organism: Homo sapiens [9606]
Fitted atomic model: 6k7g
Related EM entries by publication: EMD-9932, EMD-9933, EMD-9934, EMD-9935, EMD-9936, EMD-9937, EMD-9938, EMD-9939, EMD-9940, EMD-9941, EMD-9942
Primary publication:
Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Hiraizumi M, Yamashita K, Nishizawa T, Nureki O
Science 365 1149-1155 (2019)
PMID: 31416931

Function and Biology Details

Sample name: ATP8A1-CDC50a
Ligands: N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, CHOLESTEROL HEMISUCCINATE
Proteins: ATP8A1-CDC50a, Phospholipid-transporting ATPase, Cell cycle control protein 50A

Experimental Information Details

Resolution: 3.3Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: OTHER
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