EMDB EMD-9615

Single particle reconstruction
2.89Å resolution

Cryo-EM structure of the receptor-activated TRPC5 ion channel

Map released:
Last modified:
Overview of EMD-9615
Source organism: Mus musculus [10090]
Fitted atomic model: 6aei
Primary publication:
Cryo-EM structure of TRPC5 at 2.8- angstrom resolution reveals unique and conserved structural elements essential for channel function.
Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, Zhang C, Tian XL, Wang J, Clapham DE, Zeng B, Li Z, Zhang J
Sci Adv 5 - (2019)
PMID: 31355338

Function and Biology Details

Sample name: Mouse TRPC5
Ligands: SODIUM ION, CHOLESTEROL HEMISUCCINATE, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE
Proteins: Mouse TRPC5, Short transient receptor potential channel 5

Experimental Information Details

Resolution: 2.89Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Microscope: FEI POLARA 300
Detector: GATAN K2 IS (4k x 4k)