Single particle reconstruction
3.9Å resolution

Structure of full-length IP3R1 channel in Apo-state

Map released:
Last modified:
Overview of EMD-9248
Source organism: Rattus norvegicus [10116]
Related EM entries by publication: EMD-9243, EMD-9244, EMD-9245, EMD-9246, EMD-9247
Primary publication:
Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.
Fan G, Baker MR, Wang Z, Seryshev AB, Ludtke SJ, Baker ML, Serysheva II
Cell Res. 28 1158-1170 (2018)
PMID: 30470765

Function and Biology Details

Sample name: Inositol 1,4,5-trisphosphate receptor
Proteins: Inositol 1,4,5-trisphosphate receptor, Inositol 1,4,5-trisphosphate receptor

Experimental Information Details

Resolution: 3.9Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Reconstruction software: RELION
Microscope: FEI TECNAI F30
Detector: GATAN K2 SUMMIT (4k x 4k)