EMDB EMD-8948

Single particle reconstruction
4.05Å resolution

PDB: afTMEM16 reconstituted in nanodiscs in the presence of Ca2+

Map released:
Overview of EMD-8948
Fitted atomic model: 6e0h
Related EM entry by publication: EMD-8931, EMD-8959
Primary publication:
Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase.
Falzone ME, Rheinberger J, Lee BC, Peyear T, Sasset L, Raczkowski AM, Eng ET, Di Lorenzo A, Andersen OS, Nimigean CM, Accardi A
Elife 8 - (2019)
PMID: 30648972

Function and Biology Details

Sample name: afTMEM16 reconstituted in nanodiscs in the presence of Ca2+
Ligand: CALCIUM ION
Proteins: afTMEM16 reconstituted in nanodiscs in the presence of Ca2+, Plasma membrane channel protein (Aqy1), putative

Experimental Information Details

Resolution: 4.05Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C2
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)