EMDB EMD-8881

Single particle reconstruction
3.64Å resolution

Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed I conformation at 3.64 Angstrom resolution

Map released:
Last modified:
Overview of EMD-8881
Source organism: Mus musculus [10090]
Fitted atomic model: 5wpq
Related EM entry by publication: EMD-8882, EMD-8883
Primary publication:
Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Chen Q, She J, Zeng W, Guo J, Xu H, Bai XC, Jiang Y
Nature 550 415-418 (2017)
PMID: 29019981

Function and Biology Details

Sample name: Homotetramer of mouse TRPML1
Cellular component: Homotetramer of mouse TRPML1
Ligands: N-ACETYL-D-GLUCOSAMINE, SODIUM ION
Protein: Mucolipin-1

Experimental Information Details

Resolution: 3.64Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)