EMDB EMD-8783

Single particle reconstruction
4.0Å resolution

MERS S ectodomain trimer in complex with Fab of neutralizing antibody G4

Map released:
Last modified:
Overview of EMD-8783
Fitted atomic model: 5w9h
Primary publication:
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Pallesen J, Wang N, Corbett KS, Wrapp D, Kirchdoerfer RN, Turner HL, Cottrell CA, Becker MM, Wang L, Shi W, Kong WP, Andres EL, Kettenbach AN, Denison MR, Chappell JD, Graham BS, Ward AB, McLellan JS
Proc. Natl. Acad. Sci. U.S.A. 114 E7348-E7357 (2017)
PMID: 28807998

Function and Biology Details

Sample name: MERS S ectodomain trimer in complex with Fab of neutralizing antibody G4
Ligand: N-ACETYL-D-GLUCOSAMINE
Proteins: MERS S ectodomain trimer in complex with Fab of neutralizing antibody G4, MERS S, G4 VH, G4 VL

Experimental Information Details

Resolution: 4.0Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)