EMDB EMD-8764

Single particle reconstruction
2.94Å resolution

Cryo-electron microscopy structure of a TRPML3 ion channel

Map released:
Last modified:
Overview of EMD-8764
Source organism: Callithrix jacchus [9483]
Fitted atomic model: 5w3s
Primary publication:
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
Hirschi M, Herzik MA, Wie J, Suo Y, Borschel WF, Ren D, Lander GC, Lee SY
Nature 550 411-414 (2017)
PMID: 29019979

Function and Biology Details

Sample name: Transient Receptor Potential Mucolipin 3
Ligands: CHOLESTEROL HEMISUCCINATE, SODIUM ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, water
Proteins: Transient Receptor Potential Mucolipin 3, Mucolipin-3 isoform 1

Experimental Information Details

Resolution: 2.94Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)