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EMD-8730
Cryo-EM reconstruction of the HIV-1 BG505 SOSIP.664 Env trimer in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b
EMD-8730
Single-particle8.6 Å
Deposition: 13/05/2017Map released: 26/07/2017
Last modified: 29/01/2020
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: HIV-1 Env BG505 SOSIP.664 in complex with soluble CD4 (2-domain) and Fab domain of neutralizing 17b antibody
Deposition Authors: Lyumkis D, de Val N, Ward AB
Sample: HIV-1 Env BG505 SOSIP.664 in complex with soluble CD4 (2-domain) and Fab domain of neutralizing 17b antibody
Deposition Authors: Lyumkis D, de Val N, Ward AB
Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Ozorowski G,
Pallesen J 
,
de Val N,
Lyumkis D,
Cottrell CA,
Torres JL ,
Copps J,
Stanfield RL ,
Cupo A,
Pugach P,
Moore JP,
Wilson IA,
Ward AB
(2017) Nature , 547 , 360 - 363
,
de Val N,
Lyumkis D,
Cottrell CA,
Torres JL ,
Copps J,
Stanfield RL ,
Cupo A,
Pugach P,
Moore JP,
Wilson IA,
Ward AB
(2017) Nature , 547 , 360 - 363
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): UM1 AI100663 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): P50 GM103368 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): P01 AI110657 (United States)