EMDB EMD-8721

Single particle reconstruction
4.9Å resolution

Structure of AMPA receptor-TARP complex

Map released:
Last modified:
Overview of EMD-8721
Source organism: Rattus norvegicus [10116]
Fitted atomic model: 5vot
Related EM entry by publication: EMD-8722, EMD-8723
Primary publication:
Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Chen S, Zhao Y, Wang Y, Shekhar M, Tajkhorshid E, Gouaux E
Cell 170 1234-1246.e14 (2017)
PMID: 28823560

Function and Biology Details

Sample name: Fully occupied GluA2 AMPA receptor - TARP complex bound with quisqualate and (R,R)-2b
Proteins: Fully occupied GluA2 AMPA receptor - TARP complex bound with quisqualate and (R,R)-2b, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit

Experimental Information Details

Resolution: 4.9Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)