EMDB EMD-8643

Single particle reconstruction
4.3Å resolution

BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145

Map released:
Last modified:
Overview of EMD-8643
Source organisms:
Fitted atomic model: 5v8l
Related EM entry by publication: EMD-8644
Primary publication:
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure.
Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, Wilson IA, Burton DR, Ward AB
Immunity 46 690-702 (2017)
PMID: 28423342

Function and Biology Details

Sample name: BG505 SOSIP.664 trimer in complex with PGT145 and 3BNC117 Fabs
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: BG505 SOSIP.664 trimer in complex with PGT145 and 3BNC117 Fabs, gp120, gp41, 3BNC117 antibody, heavy chain, PGT145 antibody, heavy chain, 3BNC117 antibody, light chain, PGT145 antibody, light chain

Experimental Information Details

Resolution: 4.3Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)