Single particle reconstruction
4.1Å resolution

CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1

Map released:
Last modified:
Overview of EMD-8637
Fitted atomic model: 5v6p
Related EM entries by publication: EMD-8638, EMD-8639, EMD-8642
Primary publication:
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Schoebel S, Mi W, Stein A, Ovchinnikov S, Pavlovicz R, DiMaio F, Baker D, Chambers MG, Su H, Li D, Rapoport TA, Liao M
Nature 548 352-355 (2017)
PMID: 28682307

Function and Biology Details

Sample name: Hrd1 dimer in Hrd1/Hrd3 complex
Proteins: Hrd1 dimer in Hrd1/Hrd3 complex, ERAD-associated E3 ubiquitin-protein ligase HRD1

Experimental Information Details

Resolution: 4.1Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C2
Reconstruction software: GeRelion
Detector: GATAN K2 SUMMIT (4k x 4k)