EMD-8421
Cryo-EM structure of an asymmetric complex of BG505 DS-SOSIP HIV-1 Env trimer with vaccine elicited, fusion peptide-directed antibody vFP5.01
EMD-8421
Single-particle14.7 Å
Deposition: 05/10/2016Map released: 24/01/2018
Last modified: 20/06/2018
Sample Organism:
Human immunodeficiency virus 1
Sample: HIV-1 Env trimer
Deposition Authors: Acharya P, Kwong PD, Potter CS, Carragher B
Sample: HIV-1 Env trimer
Deposition Authors: Acharya P, Kwong PD, Potter CS, Carragher B
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Xu K,
Acharya P 
,
Kong R,
Cheng C,
Chuang GY,
Liu K ,
Louder MK ,
O'Dell S,
Rawi R,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Asokan M ,
Bailer RT,
Chambers M,
Chen X,
Choi CW,
Dandey VP,
Doria-Rose NA,
Druz A,
Eng ET ,
Farney SK,
Foulds KE,
Geng H,
Georgiev IS,
Gorman J ,
Hill KR,
Jafari AJ,
Kwon YD,
Lai YT,
Lemmin T ,
McKee K,
Ohr TY,
Ou L,
Peng D,
Rowshan AP,
Sheng Z ,
Todd JP,
Tsybovsky Y,
Viox EG,
Wang Y,
Wei H,
Yang Y,
Zhou AF,
Chen R,
Yang L,
Scorpio DG,
McDermott AB ,
Shapiro L,
Carragher B,
Potter CS,
Mascola JR,
Kwong PD
(2018) Nat. Med. , 24 , 857 - 867
,
Kong R,
Cheng C,
Chuang GY,
Liu K ,
Louder MK ,
O'Dell S,
Rawi R,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Asokan M ,
Bailer RT,
Chambers M,
Chen X,
Choi CW,
Dandey VP,
Doria-Rose NA,
Druz A,
Eng ET ,
Farney SK,
Foulds KE,
Geng H,
Georgiev IS,
Gorman J ,
Hill KR,
Jafari AJ,
Kwon YD,
Lai YT,
Lemmin T ,
McKee K,
Ohr TY,
Ou L,
Peng D,
Rowshan AP,
Sheng Z ,
Todd JP,
Tsybovsky Y,
Viox EG,
Wang Y,
Wei H,
Yang Y,
Zhou AF,
Chen R,
Yang L,
Scorpio DG,
McDermott AB ,
Shapiro L,
Carragher B,
Potter CS,
Mascola JR,
Kwong PD
(2018) Nat. Med. , 24 , 857 - 867