EMDB EMD-8290

Single particle reconstruction
11.6Å resolution

GluK2EM with LY466195

Map released:
Last modified:
Overview of EMD-8290
Source organism: Rattus norvegicus [10116]
Fitted atomic model: 5kuh
Related EM entry by publication: EMD-8289
Primary publication:
Structural basis of kainate subtype glutamate receptor desensitization.
Meyerson JR, Chittori S, Merk A, Rao P, Han TH, Serpe M, Mayer ML, Subramaniam S
Nature 537 567-571 (2016)
PMID: 27580033

Function and Biology Details

Sample name: GluK2EM with LY466195
Ligand: (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid
Proteins: GluK2EM with LY466195, Glutamate receptor ionotropic, kainate 2

Experimental Information Details

Resolution: 11.6Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)