EMDB EMD-8242

Single particle reconstruction
4.3Å resolution

EBOV GP in complex with IgG c4G7 and c13C6 Fabs

Map released:
Last modified:
Overview of EMD-8242
Source organisms:
Fitted atomic model: 5ken
Related EM entry by publication: EMD-8240, EMD-8241
Primary publication:
Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB
Nat Microbiol 1 16128-16128 (2016)
PMID: 27562261

Function and Biology Details

Sample name: Ebola virus trimeric surface glycoprotein in complex with IgG c4G7 and c13C6 Fabs
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: Ebola virus trimeric surface glycoprotein in complex with IgG c4G7 and c13C6 Fabs, Ebola surface glycoprotein, GP1, Ebola surface glycoprotein, GP2, c4G7 variable Fab domain heavy chain, c4G7 variable Fab domain light chain, c13C6 variable Fab domain light chain, c13C6 variable Fab domain heavy chain

Experimental Information Details

Resolution: 4.3Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)