EMDB EMD-8215

Single particle reconstruction
3.78Å resolution

Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin

Map released:
Last modified:
Overview of EMD-8215
Source organisms:
Fitted atomic model: 5k7l
Primary publication:
Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism.
Whicher JR, MacKinnon R
Science 353 664-669 (2016)
PMID: 27516594

Function and Biology Details

Sample name: Voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin
Cellular components: Voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin, Voltage-gated potassium channel Eag1, Calmodulin
Ligands: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE
Proteins: Potassium voltage-gated channel subfamily H member 1, Calmodulin

Experimental Information Details

Resolution: 3.78Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Reconstruction software: FREALIGN
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)