EMDB EMD-8191

Single particle reconstruction
2.8Å resolution

Cryo-EM structure of lactate dehydrogenase (LDH) in complex with GSK2837808A

Map released:
Last modified:
Overview of EMD-8191
Source organism: Gallus gallus [9031]
Fitted atomic model: 5k0z
Related EM entries by publication: EMD-8192, EMD-8193, EMD-8194
Primary publication:
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Merk A, Bartesaghi A, Banerjee S, Falconieri V, Rao P, Davis MI, Pragani R, Boxer MB, Earl LA, Milne JL, Subramaniam S
Cell 165 1698-1707 (2016)
PMID: 27238019

Function and Biology Details

Sample name: Lactate dehydrogenase (LDH) in complex with GSK2837808A
Ligand: water
Proteins: Lactate dehydrogenase (LDH) in complex with GSK2837808A, L-lactate dehydrogenase B chain

Experimental Information Details

Resolution: 2.8Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: D2
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)