Single particle reconstruction
3.43Å resolution

Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc

Map released:
Last modified:
Overview of EMD-8119
Source organism: Rattus norvegicus [10116]
Fitted atomic model: 5is0
Related EM entries by publication: EMD-8117, EMD-8118, EMD-8120
Primary publication:
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Gao Y, Cao E, Julius D, Cheng Y
Nature 534 347-351 (2016)
PMID: 27281200

Function and Biology Details

Sample name: TRPV1 ion channel in complex with capsazepine
Ligand: capsazepine
Proteins: TRPV1 ion channel in complex with capsazepine, Transient receptor potential cation channel subfamily V member 1

Experimental Information Details

Resolution: 3.43Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Reconstruction software: RELION
Microscope: FEI POLARA 300
Detector: GATAN K2 SUMMIT (4k x 4k)