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EMD-8092

Single-particle
16.0 Å
EMD-8092
3D View Gallery
Deposition: 28/02/2016
Map released: 13/04/2016
Last modified: 15/06/2016
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8092
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Structure of the quaternary complex of complement C5 with two tick inhibitors (OmCI and RaCI) and a Fab derived from the therapeutic Eculizumab

EMD-8092

Single-particle
16.0 Å
EMD-8092
3D View Gallery
Deposition: 28/02/2016
Map released: 13/04/2016
Last modified: 15/06/2016
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rhipicephalus appendiculatus, Human, Synthetic construct
Sample: Complex of Complement C5 with two tick inihibitors and Fab fragment derived from Eculizumab

Deposition Authors: Lea SM, Elmlund H
Structural basis for therapeutic inhibition of complement C5.
Jore MM, Johnson S , Sheppard D, Barber NM , Li YI , Nunn MA, Elmlund H , Lea SM
(2016) Nat. Struct. Mol. Biol. , 23 , 378 - 386
PUBMED: 27018802
DOI: doi:10.1038/nsmb.3196
ISSN: 1545-9985