EMD-80449

Single-particle
3.01 Å
EMD-80449
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80449

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-25xn summary report (pdf.gz) Map-25xn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the Crimean-Congo hemorrhagic fever virus full-length L protein RdRP elongation complex (EC14 form)

EMD-80449

Single-particle
3.01 Å
EMD-80449
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Orthonairovirus haemorrhagiae
Sample: Crimean-Congo hemorrhagic fever virus RNA-dependent RNA polymerase elongation complex
Fitted models: 25xn

Deposition Authors: Jia H , Tang B, Gong P
RNA synthesis and substrate analogue inhibition in the CCHFV polymerase.
Jia H , Tang B, Liu S, Wen X, Wu F, Hu X, Zhou H, Chong T, Lv L, Liu Q, Rao G, Wei M, Jing X, Cao S , Deng F , Hu Z , Shu B, Gong R , Wu J, Wang M , Gong P
(2026) Nature
PUBMED: 42649282
DOI: doi:10.1038/s41586-026-10913-w
ISSN: 1476-4687
ASTM: NATUAS