EMD-80448

Single-particle
2.67 Å
EMD-80448
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80448

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-25xm summary report (pdf.gz) Map-25xm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the Crimean-Congo hemorrhagic fever virus L protein (5'-cRNA-bound form)

EMD-80448

Single-particle
2.67 Å
EMD-80448
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Orthonairovirus haemorrhagiae, synthetic construct
Sample: the Crimean-Congo hemorrhagic fever virus L protein in complex with a 14-nt 5'-cRNA
Fitted models: 25xm

Deposition Authors: Jia H , Liu S, Gong P
RNA synthesis and substrate analogue inhibition in the CCHFV polymerase.
Jia H , Tang B, Liu S, Wen X, Wu F, Hu X, Zhou H, Chong T, Lv L, Liu Q, Rao G, Wei M, Jing X, Cao S , Deng F , Hu Z , Shu B, Gong R , Wu J, Wang M , Gong P
(2026) Nature
PUBMED: 42649282
DOI: doi:10.1038/s41586-026-10913-w
ISSN: 1476-4687
ASTM: NATUAS