EMD-80447

Single-particle
2.88 Å
EMD-80447
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80447

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-25xl summary report (pdf.gz) Map-25xl FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the Crimean-Congo hemorrhagic fever virus L protein (apo form)

EMD-80447

Single-particle
2.88 Å
EMD-80447
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Orthonairovirus haemorrhagiae
Sample: Crimean-Congo hemorrhagic fever virus L protein
Fitted models: 25xl

Deposition Authors: Jia H, Liu S, Gong P
RNA synthesis and substrate analog inhibition in the CCHFV polymerase
Jia H, Tang B, Liu S, Wen X, Wu F, Hu X, Zhou H, Chong T, Lv L, Liu Q, Rao G, Wei M, Jing X, Cao S, Deng F, Hu Z, Shu B, Gong R, Wu J, Wang M, Gong P
(2026) Nature
DOI: doi:10.1038/s41586-026-10913-w
ISSN: 1476-4687
ASTM: NATUAS