EMD-80237

Single-particle
3.21 Å
EMD-80237 Deposition: 10/04/2026
Map released: 03/06/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80237

A complex of PTH1R/Gs bound to a PTHrP analogue with five beta-amino acids

EMD-80237

Single-particle
3.21 Å
EMD-80237 Deposition: 10/04/2026
Map released: 03/06/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama, synthetic construct
Sample: Complex containing PTH1R and Gs heterotrimer
Fitted models: 25nv

Deposition Authors: Cary BP, Wootten D, Sexton PM, Gellman SH, Wook TK, Shin J, Gerrard EJ
Altered Intracellular Trafficking as a Mechanism for Prolonged Duration of G Protein-Coupled Receptor Activation.
Kim TW, Gerrard EJ, Shin J, Gardella TJ, Wootten D, Sexton PM, Cary BP, Gellman SH
(2026) J Am Chem Soc , 148 , 22045 - 22061
PUBMED: 42159093
DOI: doi:10.1021/jacs.6c02192
ISSN: 1520-5126
ASTM: JACSAT